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Figure 1
Structure of UrdA at cryogenic and room temperatures. (a) Cartoon representation of the RT structure of UrdA showing the FAD domain (yellow) and clamp domain (green), with bound substrate (red circle) and the catalytic Arg411 shown as sticks. (b) Superimposition of the UrdA′S-RT (beige) and UrdA′S-cryo (light purple; PDB entry 6t87) structures using the FAD domain. An enlargement of the active site is also shown. Substrate is marked S. (c) Active site of the UrdA′S-RT structure with a 2mFoDFc map shown at 1σ and hydrogen bonds shown as dashed lines. Substrate (urocanate) is marked S.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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