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Figure 1
Model system, target ligand and structural homology between selective cephalosporins. (a) CTX-M-14 β-lactamase. The catalytically important active-site residue Ser70 and the functionally relevant Ω loop (residues 160–180) are highlighted. (b) Cefdinir in the active site of CTX-M-14 E166A. (c) Ceftriaxone. (d) Cefotaxime. (e) Ceftazidime. (f) Cefdinir. Differences in the side chain are highlighted.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 82| Part 6| June 2026| Pages 672-682
https://doi.org/10.1107/S2059798326003992
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