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Figure 3
MR/MRSAD phasing protocol in Auto-Rickshaw. The workflow combines a molecular-replacement branch, in which a search model is used to obtain and validate an MR solution, with an experimental anomalous, isomorphous or RIP branch, in which signal analysis and difference-map interpretation identify useful experimental sites. The MR-derived phases or partial model and the experimental sites are combined in the MR-assisted experimental phasing core, followed by dual-space fragment phasing, phase combination, density modification, model building and refinement. |
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menu![[Figure 3]](he5698fig3.jpg)