forthcoming articles

The structure of the N-terminal actin-binding domain of human dystrophin was determined, revealing a closed conformation with the first and second calponin homology domains directly interacting.

The ManifoldEM method for conformational heterogeneity analysis in single-particle cryo-EM was first presented nearly a decade ago; however, its accessibility to a wide audience has been limited. Here, we describe a step-by-step breakdown accompanied by a modern Python implementation with increased usability, enhanced performance and improved accessibility to future feature additions.

Five GH20-family dispersins were characterized for activity on aryl glycosides and poly-β-1,6-linked N-acetyl-D-glucosamine oligomers and three crystal structures were solved, including two complexes with bound inhibitors.