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organic compounds\(\def\hfill{\hskip 5em}\def\hfil{\hskip 3em}\def\eqno#1{\hfil {#1}}\)

Journal logoCRYSTALLOGRAPHIC
COMMUNICATIONS
ISSN: 2056-9890
Volume 66| Part 9| September 2010| Page o2279
https://doi.org/10.1107/S1600536810031363

2-(2-Meth­­oxy-5-methyl­phen­yl)-2H-benzotriazole

Ming-Jen Chen,a Chen-Yu Li,b Chen-Yen Tsaib and Bao-Tsan Kob*

aDepartment of Applied Cosmetology and Graduate Institute of Cosmetic Science, Hungkuang University, Taichung Hsien 433, Taiwan, and bDepartment of Chemistry, Chung Yuan Christian University, Chung-Li 320, Taiwan
*Correspondence e-mail: btko@cycu.edu.tw

(Received 27 July 2010; accepted 5 August 2010; online 11 August 2010)

In the title mol­ecule, C14H13N3O, the dihedral angle between the mean planes of the benzotriazole ring system and the benzene ring is 57.8 (2)°.

Related literature

For related structures, see: Li et al. (2009[Li, J.-Y., Liu, Y.-C., Lin, C.-H. & Ko, B.-T. (2009). Acta Cryst. E65, o2475.], 2010[Li, C.-Y., Tsai, C.-Y., Lin, C.-H. & Ko, B.-T. (2010). Acta Cryst. E66, o726.]); Liu et al. (2009[Liu, Y.-C., Lin, C.-H. & Ko, B.-T. (2009). Acta Cryst. E65, o2058.]).

[Scheme 1]

Experimental

Crystal data

  • C14H13N3O

  • Mr = 239.27

  • Monoclinic, P 21

  • a = 7.1604 (2) Å

  • b = 8.2560 (2) Å

  • c = 11.0342 (3) Å

  • β = 103.450 (1)°

  • V = 634.41 (3) Å3

  • Z = 2

  • Mo Kα radiation

  • μ = 0.08 mm−1

  • T = 296 K

  • 0.48 × 0.32 × 0.17 mm
Data collection

  • Bruker APEXII CCD diffractometer

  • Absorption correction: multi-scan (SADABS; Bruker, 2008[Bruker (2008). APEX2, SAINT-Plus and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]) Tmin = 0.962, Tmax = 0.986

  • 6057 measured reflections

  • 1674 independent reflections

  • 1401 reflections with I > 2σ(I)

  • Rint = 0.021
Refinement

  • R[F2 > 2σ(F2)] = 0.046

  • wR(F2) = 0.136

  • S = 1.05

  • 1674 reflections

  • 164 parameters

  • 1 restraint

  • H-atom parameters constrained

  • Δρmax = 0.17 e Å−3

  • Δρmin = −0.15 e Å−3

Data collection: APEX2 (Bruker, 2008[Bruker (2008). APEX2, SAINT-Plus and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]); cell refinement: SAINT (Bruker, 2008[Bruker (2008). APEX2, SAINT-Plus and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008[Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.]); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008[Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.]); molecular graphics: SHELXTL (Sheldrick, 2008[Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.]); software used to prepare material for publication: SHELXTL.

Supporting information

Crystal structure: contains datablocks I, global. DOI: https://doi.org/10.1107/S1600536810031363/lh5100sup1.cif

Structure factors: contains datablock I. DOI: https://doi.org/10.1107/S1600536810031363/lh5100Isup2.hkl

checkCIF report


Comment top

In terms of coordination chemistry, the benzotriazole-phenolate (BTP) group can provide the N, O-bidentate chelation to stabilize transition metal or main group metal complexes. Therefore, our group is focused on the design and synthesis of the functionalized benzotriazole-phenolate ligand derived from 4-methyl-2-(2H-benzotriazol-2-yl)phenol (MeBTP-H). For instance, our group has successfully synthesized and structural characterized the amino-phenolate ligand via a Mannich condensation derived from MeBTP-H (Li et al., 2009). Most recently, we also reported the synthesis and crystal structure of the salicylaldehyde group substituted benzotriazole derivative (Li et al., 2010). In order to develop more useful ligands originated from BTP derivatives, we report herein the synthesis and crystal structure of the title compound, (I), a potential ligand for the preparation of orthometallated IrIII or PdII complexes.

The molecular structure of (I) is shown in Fig. 1. The dihedral angle between the mean planes of the benzotriazole unit and the benzene ring of the 2-methoxy-5-methylphenyl group is 57.8 (2)°, which is larger than that found in the crystal structure of 2-(2H-Benzotriazol-2-yl)-4-methylphenyl diphenylphosphinate (Liu et al., 2009).

Related literature top

For related structures, see: Li et al. (2009, 2010); Liu et al. (2009).

Experimental top

The title compound (I) was synthesized by the procedure shown in Fig. 2. A mixture of 4-methyl-2-(2H-benzotriazol-2-yl)phenol (2.48 g, 10.0 mmol) and potassium carbonate (1.40 g, 10.0 mmol) in THF (30 ml) was stirred at room temperature for 0.5 h. Dimethyl sulfate (1.90 g, 15.0 mmol) was then added and the resulting mixture was refluxed for another 24 h. The mixture was filtered and the filtrate was dried in vacuo giving white powder. The white powder was redissolved in hexane and cooled to 253 K to give white crystalline solids. Colourless crystals were obtained from the saturated Et2O solution overnight. 1H NMR (CDCl3, p.p.m.): δ 7.01–7.97 (7H, m, PhH), 3.84 (3H, s, OCH3), 2.36 (3H, s, CH3).

Refinement top

In the absence of significant anomalous dispersion effects the Friedel pairs were merged. The H atoms were placed in idealized positions and constrained to ride on their parent atoms, with C–H = 0.93 Å with Uiso(H) = 1.2 Ueq(C) for phenyl hydrogen; 0.96 Å with Uiso(H) = 1.5 Ueq(C) for the CH3 groups.

Structure description top

In terms of coordination chemistry, the benzotriazole-phenolate (BTP) group can provide the N, O-bidentate chelation to stabilize transition metal or main group metal complexes. Therefore, our group is focused on the design and synthesis of the functionalized benzotriazole-phenolate ligand derived from 4-methyl-2-(2H-benzotriazol-2-yl)phenol (MeBTP-H). For instance, our group has successfully synthesized and structural characterized the amino-phenolate ligand via a Mannich condensation derived from MeBTP-H (Li et al., 2009). Most recently, we also reported the synthesis and crystal structure of the salicylaldehyde group substituted benzotriazole derivative (Li et al., 2010). In order to develop more useful ligands originated from BTP derivatives, we report herein the synthesis and crystal structure of the title compound, (I), a potential ligand for the preparation of orthometallated IrIII or PdII complexes.

The molecular structure of (I) is shown in Fig. 1. The dihedral angle between the mean planes of the benzotriazole unit and the benzene ring of the 2-methoxy-5-methylphenyl group is 57.8 (2)°, which is larger than that found in the crystal structure of 2-(2H-Benzotriazol-2-yl)-4-methylphenyl diphenylphosphinate (Liu et al., 2009).

For related structures, see: Li et al. (2009, 2010); Liu et al. (2009).

Computing details top

Data collection: APEX2 (Bruker, 2008); cell refinement: SAINT (Bruker, 2008); data reduction: SAINT (Bruker, 2008); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXTL (Sheldrick, 2008).

Figures top
[Figure 1] Fig. 1. The molecular structure of I with the atom numbering scheme. Displacement ellipsoids are drawn at the 30% probability level.
[Figure 2] Fig. 2. The synthetic procedure of I.
2-(2-Methoxy-5-methylphenyl)-2H-benzotriazole top
Crystal data top
C14H13N3OF(000) = 252
Mr = 239.27Dx = 1.253 Mg m−3
Monoclinic, P21Mo Kα radiation, λ = 0.71073 Å
Hall symbol: P 2ybCell parameters from 3727 reflections
a = 7.1604 (2) Åθ = 2.9–28.2°
b = 8.2560 (2) ŵ = 0.08 mm−1
c = 11.0342 (3) ÅT = 296 K
β = 103.450 (1)°Columnar, colourless
V = 634.41 (3) Å30.48 × 0.32 × 0.17 mm
Z = 2
Data collection top
Bruker APEXII CCD
diffractometer		1674 independent reflections
Radiation source: fine-focus sealed tube1401 reflections with I > 2σ(I)
Graphite monochromatorRint = 0.021
Detector resolution: 8.3333 pixels mm-1θmax = 28.3°, θmin = 1.9°
φ and ω scansh = −8→9
Absorption correction: multi-scan
(SADABS; Bruker, 2008)		k = −11→11
Tmin = 0.962, Tmax = 0.986l = −14→14
6057 measured reflections
Refinement top
Refinement on F2Secondary atom site location: difference Fourier map
Least-squares matrix: fullHydrogen site location: inferred from neighbouring sites
R[F2 > 2σ(F2)] = 0.046H-atom parameters constrained
wR(F2) = 0.136 w = 1/[σ2(Fo2) + (0.0703P)2 + 0.098P]
where P = (Fo2 + 2Fc2)/3
S = 1.05(Δ/σ)max < 0.001
1674 reflectionsΔρmax = 0.17 e Å−3
164 parametersΔρmin = −0.15 e Å−3
1 restraintExtinction correction: SHELXL97 (Sheldrick, 2008), Fc*=kFc[1+0.001xFc2λ3/sin(2θ)]-1/4
Primary atom site location: structure-invariant direct methodsExtinction coefficient: 0.067 (13)
Crystal data top
C14H13N3OV = 634.41 (3) Å3
Mr = 239.27Z = 2
Monoclinic, P21Mo Kα radiation
a = 7.1604 (2) ŵ = 0.08 mm−1
b = 8.2560 (2) ÅT = 296 K
c = 11.0342 (3) Å0.48 × 0.32 × 0.17 mm
β = 103.450 (1)°
Data collection top
Bruker APEXII CCD
diffractometer		1674 independent reflections
Absorption correction: multi-scan
(SADABS; Bruker, 2008)		1401 reflections with I > 2σ(I)
Tmin = 0.962, Tmax = 0.986Rint = 0.021
6057 measured reflections
Refinement top
R[F2 > 2σ(F2)] = 0.0461 restraint
wR(F2) = 0.136H-atom parameters constrained
S = 1.05Δρmax = 0.17 e Å−3
1674 reflectionsΔρmin = −0.15 e Å−3
164 parameters
Special details top

Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes.

Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2) top
xyzUiso*/Ueq
O0.4845 (3)0.6862 (5)0.1130 (2)0.1062 (12)
N10.3698 (3)0.9600 (4)0.2453 (2)0.0707 (7)
N20.2199 (3)0.8702 (3)0.19219 (18)0.0547 (5)
N30.0939 (3)0.8349 (3)0.25880 (19)0.0610 (6)
C10.3261 (4)0.7274 (4)0.0259 (2)0.0661 (8)
C20.1880 (4)0.8191 (4)0.0643 (2)0.0551 (6)
C30.0210 (4)0.8665 (4)−0.0174 (2)0.0563 (6)
H3B−0.06890.92790.01130.068*
C4−0.0144 (4)0.8234 (4)−0.1425 (2)0.0602 (7)
C50.1215 (5)0.7297 (4)−0.1801 (2)0.0668 (8)
H5A0.09950.6976−0.26300.080*
C60.2882 (5)0.6826 (5)−0.0987 (3)0.0720 (8)
H6A0.37680.6198−0.12740.086*
C70.3395 (4)0.9863 (4)0.3605 (2)0.0638 (7)
C80.4473 (6)1.0761 (6)0.4615 (3)0.0895 (11)
H8A0.56131.12740.45740.107*
C90.3761 (6)1.0840 (5)0.5651 (3)0.0949 (13)
H9A0.44391.14190.63360.114*
C100.2044 (8)1.0082 (6)0.5726 (3)0.1011 (13)
H10A0.16201.01800.64580.121*
C110.0972 (7)0.9208 (6)0.4769 (3)0.0900 (11)
H11A−0.01720.87150.48250.108*
C120.1694 (4)0.9090 (4)0.3677 (2)0.0609 (7)
C13−0.1948 (5)0.8824 (5)−0.2321 (3)0.0846 (10)
H13A−0.27010.9448−0.18750.127*
H13B−0.26830.7911−0.27070.127*
H13C−0.16050.9487−0.29510.127*
C140.6487 (5)0.6546 (7)0.0835 (4)0.0985 (14)
H14A0.74390.62770.15750.148*
H14B0.68960.74810.04480.148*
H14C0.63210.56490.02660.148*
Atomic displacement parameters (Å2) top
U11U22U33U12U13U23
O0.0727 (13)0.190 (4)0.0590 (11)0.0505 (19)0.0224 (10)0.0159 (18)
N10.0598 (13)0.096 (2)0.0548 (12)−0.0144 (13)0.0095 (10)−0.0005 (13)
N20.0544 (11)0.0688 (14)0.0417 (9)−0.0028 (10)0.0126 (8)0.0001 (9)
N30.0703 (13)0.0706 (14)0.0464 (10)−0.0090 (12)0.0222 (9)−0.0029 (10)
C10.0627 (15)0.089 (2)0.0502 (13)0.0096 (16)0.0203 (11)0.0099 (14)
C20.0568 (13)0.0702 (16)0.0403 (10)−0.0049 (12)0.0154 (9)−0.0003 (11)
C30.0576 (13)0.0615 (15)0.0495 (12)−0.0047 (12)0.0122 (10)−0.0021 (11)
C40.0687 (15)0.0617 (15)0.0475 (11)−0.0131 (13)0.0080 (10)0.0025 (12)
C50.089 (2)0.0702 (17)0.0435 (12)−0.0138 (16)0.0213 (12)−0.0059 (12)
C60.085 (2)0.084 (2)0.0560 (14)0.0083 (17)0.0333 (14)−0.0004 (15)
C70.0725 (16)0.0697 (17)0.0443 (12)−0.0040 (14)0.0037 (11)0.0046 (12)
C80.094 (2)0.103 (3)0.0595 (17)−0.018 (2)−0.0068 (15)−0.0009 (19)
C90.134 (3)0.094 (3)0.0441 (14)−0.012 (3)−0.0043 (17)−0.0044 (16)
C100.166 (4)0.094 (3)0.0461 (15)−0.013 (3)0.0296 (19)−0.0035 (16)
C110.129 (3)0.094 (2)0.0549 (16)−0.021 (2)0.0374 (18)−0.0089 (17)
C120.0783 (17)0.0611 (15)0.0427 (11)−0.0037 (13)0.0132 (11)0.0039 (11)
C130.090 (2)0.095 (3)0.0565 (15)−0.009 (2)−0.0091 (14)−0.0017 (17)
C140.0672 (19)0.143 (4)0.091 (2)0.017 (2)0.0301 (17)0.015 (3)
Geometric parameters (Å, º) top
O—C141.317 (4)C7—C121.393 (4)
O—C11.348 (3)C7—C81.410 (4)
N1—N21.324 (3)C8—C91.357 (5)
N1—C71.355 (4)C8—H8A0.9300
N2—N31.322 (3)C9—C101.399 (6)
N2—C21.439 (3)C9—H9A0.9300
N3—C121.345 (3)C10—C111.360 (6)
C1—C21.387 (4)C10—H10A0.9300
C1—C61.389 (4)C11—C121.421 (4)
C2—C31.377 (4)C11—H11A0.9300
C3—C41.391 (4)C13—H13A0.9600
C3—H3B0.9300C13—H13B0.9600
C4—C51.380 (4)C13—H13C0.9600
C4—C131.513 (4)C14—H14A0.9600
C5—C61.372 (4)C14—H14B0.9600
C5—H5A0.9300C14—H14C0.9600
C6—H6A0.9300
C14—O—C1121.7 (2)C9—C8—C7116.6 (4)
N2—N1—C7102.4 (2)C9—C8—H8A121.7
N3—N2—N1117.7 (2)C7—C8—H8A121.7
N3—N2—C2120.5 (2)C8—C9—C10122.5 (3)
N1—N2—C2121.7 (2)C8—C9—H9A118.8
N2—N3—C12102.2 (2)C10—C9—H9A118.8
O—C1—C2117.5 (2)C11—C10—C9122.4 (4)
O—C1—C6125.2 (3)C11—C10—H10A118.8
C2—C1—C6117.3 (3)C9—C10—H10A118.8
C3—C2—C1121.9 (2)C10—C11—C12116.4 (4)
C3—C2—N2118.3 (2)C10—C11—H11A121.8
C1—C2—N2119.8 (2)C12—C11—H11A121.8
C2—C3—C4120.5 (3)N3—C12—C7109.4 (2)
C2—C3—H3B119.8N3—C12—C11129.7 (3)
C4—C3—H3B119.8C7—C12—C11120.8 (3)
C5—C4—C3117.6 (3)C4—C13—H13A109.5
C5—C4—C13122.6 (3)C4—C13—H13B109.5
C3—C4—C13119.8 (3)H13A—C13—H13B109.5
C6—C5—C4121.9 (2)C4—C13—H13C109.5
C6—C5—H5A119.0H13A—C13—H13C109.5
C4—C5—H5A119.0H13B—C13—H13C109.5
C5—C6—C1120.8 (3)O—C14—H14A109.5
C5—C6—H6A119.6O—C14—H14B109.5
C1—C6—H6A119.6H14A—C14—H14B109.5
N1—C7—C12108.2 (2)O—C14—H14C109.5
N1—C7—C8130.4 (3)H14A—C14—H14C109.5
C12—C7—C8121.4 (3)H14B—C14—H14C109.5
C7—N1—N2—N30.3 (3)C13—C4—C5—C6177.3 (3)
C7—N1—N2—C2177.1 (3)C4—C5—C6—C10.3 (5)
N1—N2—N3—C12−0.2 (3)O—C1—C6—C5179.4 (3)
C2—N2—N3—C12−177.0 (2)C2—C1—C6—C50.9 (5)
C14—O—C1—C2−154.6 (4)N2—N1—C7—C12−0.3 (3)
C14—O—C1—C626.9 (7)N2—N1—C7—C8−178.9 (4)
O—C1—C2—C3−179.7 (3)N1—C7—C8—C9178.0 (4)
C6—C1—C2—C3−1.0 (5)C12—C7—C8—C9−0.4 (5)
O—C1—C2—N21.8 (4)C7—C8—C9—C10−0.3 (6)
C6—C1—C2—N2−179.5 (3)C8—C9—C10—C110.3 (7)
N3—N2—C2—C356.9 (4)C9—C10—C11—C120.4 (7)
N1—N2—C2—C3−119.8 (3)N2—N3—C12—C70.0 (3)
N3—N2—C2—C1−124.6 (3)N2—N3—C12—C11177.5 (4)
N1—N2—C2—C158.8 (4)N1—C7—C12—N30.2 (4)
C1—C2—C3—C4−0.1 (4)C8—C7—C12—N3178.9 (3)
N2—C2—C3—C4178.5 (3)N1—C7—C12—C11−177.6 (3)
C2—C3—C4—C51.2 (4)C8—C7—C12—C111.1 (5)
C2—C3—C4—C13−177.5 (3)C10—C11—C12—N3−178.4 (4)
C3—C4—C5—C6−1.3 (5)C10—C11—C12—C7−1.1 (6)

Experimental details

Crystal data
Chemical formulaC14H13N3O
Mr239.27
Crystal system, space groupMonoclinic, P21
Temperature (K)296
a, b, c (Å)7.1604 (2), 8.2560 (2), 11.0342 (3)
β (°) 103.450 (1)
V (Å3)634.41 (3)
Z2
Radiation typeMo Kα
µ (mm−1)0.08
Crystal size (mm)0.48 × 0.32 × 0.17
Data collection
DiffractometerBruker APEXII CCD
Absorption correctionMulti-scan
(SADABS; Bruker, 2008)
Tmin, Tmax0.962, 0.986
No. of measured, independent and
observed [I > 2σ(I)] reflections		6057, 1674, 1401
Rint0.021
(sin θ/λ)max (Å−1)0.667
Refinement
R[F2 > 2σ(F2)], wR(F2), S 0.046, 0.136, 1.05
No. of reflections1674
No. of parameters164
No. of restraints1
H-atom treatmentH-atom parameters constrained
Δρmax, Δρmin (e Å−3)0.17, −0.15

Computer programs: APEX2 (Bruker, 2008), SAINT (Bruker, 2008), SHELXS97 (Sheldrick, 2008), SHELXL97 (Sheldrick, 2008), SHELXTL (Sheldrick, 2008).

 

Acknowledgements

We gratefully acknowledge financial support in part from the National Science Council, Taiwan (NSC99–2113-M-033–007-MY2) and in part from the CYCU Distinctive Research Area project in the Chung Yuan Christian University, Taiwan (CYCU–98–CR–CH).

References

First citationBruker (2008). APEX2, SAINT-Plus and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.  Google Scholar
 First citationLi, J.-Y., Liu, Y.-C., Lin, C.-H. & Ko, B.-T. (2009). Acta Cryst. E65, o2475.  Web of Science CSD CrossRef IUCr Journals Google Scholar
 First citationLi, C.-Y., Tsai, C.-Y., Lin, C.-H. & Ko, B.-T. (2010). Acta Cryst. E66, o726.  Web of Science CrossRef IUCr Journals Google Scholar
 First citationLiu, Y.-C., Lin, C.-H. & Ko, B.-T. (2009). Acta Cryst. E65, o2058.  Web of Science CSD CrossRef IUCr Journals Google Scholar
 First citationSheldrick, G. M. (2008). Acta Cryst. A64, 112–122.  Web of Science CrossRef CAS IUCr Journals Google Scholar

This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.

Journal logoCRYSTALLOGRAPHIC
COMMUNICATIONS
ISSN: 2056-9890
Volume 66| Part 9| September 2010| Page o2279
https://doi.org/10.1107/S1600536810031363
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