2-Benzhydryl-6-tert-butyl-4-methyl­phenol

Yoon, S.; Lee, J.; Kim, Y.

doi:10.1107/S1600536813002006

organic compounds

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ISSN: 2056-9890

Volume 69| Part 2| February 2013| Page o287

doi:10.1107/S1600536813002006

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2-Benzhydryl-6-tert-butyl-4-methylphenol

Sungwoo Yoon,^a Junseong Lee ^b and Youngjo Kim ^a ^*

^aDepartment of Chemistry, Chungbuk National University, Cheongju, Chungbuk 361-763, Republic of Korea, and ^bDepartment of Chemistry, Chonnam National University, Gwangju 500-757, Republic of Korea
^*Correspondence e-mail: ykim@chungbuk.ac.kr

(Received 28 November 2012; accepted 21 January 2013; online 26 January 2013)

The title compound, C₂₄H₂₆O, was prepared by the reaction between 2-tert-butyl-4-methylphenol and diphenylmethanol in the presence of sulfuric acid. Three benzene rings are attached directly to the central C—H group in a twisted propeller conformation with the local pseudo-C₃ rotational axis coinciding with the C—H bond. There are three short C—H⋯O contacts in the molecule.

Related literature

For similar structure types, see: Kim et al. (2012 ).

Experimental

Crystal data

C₂₄H₂₆O
M_r = 330.45
Monoclinic, P 2₁ /n
a = 8.014 (4) Å
b = 15.472 (7) Å
c = 16.006 (7) Å
β = 99.98 (2)°
V = 1954.6 (15) Å³
Z = 4
Mo Kα radiation
μ = 0.07 mm⁻¹
T = 296 K
0.20 × 0.17 × 0.15 mm

Data collection

Bruker APEXII CCD diffractometer
Absorption correction: multi-scan (SADABS; Bruker, 2009 ) T_min = 0.987, T_max = 0.990
17522 measured reflections
3422 independent reflections
1532 reflections with I > 2σ(I)
R_int = 0.138

Refinement

R[F² > 2σ(F²)] = 0.071
wR(F²) = 0.172
S = 1.00
3422 reflections
231 parameters
H-atom parameters constrained
Δρ_max = 0.15 e Å⁻³
Δρ_min = −0.21 e Å⁻³

Table 1
Hydrogen-bond geometry (Å, °)

D—H⋯A	D—H	H⋯A	D⋯A	D—H⋯A
C8—H8C⋯O	0.96	2.41	3.049 (4)	123
C10—H10A⋯O	0.96	2.44	3.071 (5)	123
C12—H12⋯O	0.98	2.38	2.771 (4)	103

Data collection: APEX2 (Bruker, 2009); cell refinement: SAINT (Bruker, 2009); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008 ); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXTL.

Supporting information

Crystal structure: contains datablocks I, global. DOI: 10.1107/S1600536813002006/kj2218sup1.cif

Structure factors: contains datablock I. DOI: 10.1107/S1600536813002006/kj2218Isup2.hkl

Supporting information file. DOI: 10.1107/S1600536813002006/kj2218Isup3.cdx

Supporting information file. DOI: 10.1107/S1600536813002006/kj2218Isup4.cml

checkCIF report

Comment top

The molecular structure of the title compound, C₂₄H₂₆O, is shown in Figure 1. The C—O and C—C bond lengths in the phenol ring and two phenyl rings are in the range of typical values determined on similar compounds (Kim et al. 2012). The three aromatic rings are twisted and form a propeller conformation with the local pseudo-C₃ rotational axis coinciding with C12—H12. The orientation of the rings can be characterized by the torsion angles H12-C12-C2-C1 (-35 °), H12-C12-C19-C24 (-59 °) and H12-C12-C13-C14 (-26 °). The molecules display three intramolecular C—H···O contacts (geometric details are given in Table 1), but no intermolecular hydrogen bonds are present.

Related literature top

For similar structure types, see: Kim et al. (2012).

Experimental top

The title compound could be isolated in 94% yield via the reaction of sulfuric acid, 2-tert-butyl-4-methylphenol, and diphenylmethanol in glacial acetic acid. The crystal was obtained by slow evaporation of solvent in refrigerator.

Computing details top

Data collection: APEX2 (Bruker, 2009); cell refinement: SAINT (Bruker, 2009); data reduction: SAINT (Bruker, 2009); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXTL (Sheldrick, 2008).

Figures top

Fig. 1. Molecular structure of the title compound, with the atom-numbering scheme. Displacement ellipsoids are drawn at the 50% probability level. H atoms, with exception of H12 and H0, are omitted for clarity.

2-Benzhydryl-6-tert-butyl-4-methylphenol top

Crystal data top

C₂₄H₂₆O	F(000) = 712
M_r = 330.45	D_x = 1.123 Mg m⁻³
Monoclinic, P2₁/n	Mo Kα radiation, λ = 0.71073 Å
a = 8.014 (4) Å	Cell parameters from 925 reflections
b = 15.472 (7) Å	θ = 2.7–16.4°
c = 16.006 (7) Å	µ = 0.07 mm⁻¹
β = 99.98 (2)°	T = 296 K
V = 1954.6 (15) Å³	Block, colorless
Z = 4	0.20 × 0.17 × 0.15 mm

Data collection top

Bruker APEXII CCD diffractometer	3422 independent reflections
Radiation source: fine-focus sealed tube	1532 reflections with I > 2σ(I)
Graphite monochromator	R_int = 0.138
ϕ and ω scans	θ_max = 25.0°, θ_min = 2.6°
Absorption correction: multi-scan (SADABS; Bruker, 2009)	h = −9→9
T_min = 0.987, T_max = 0.990	k = −17→17
17522 measured reflections	l = −18→19

Refinement top

Refinement on F²	Primary atom site location: structure-invariant direct methods
Least-squares matrix: full	Secondary atom site location: difference Fourier map
R[F² > 2σ(F²)] = 0.071	Hydrogen site location: inferred from neighbouring sites
wR(F²) = 0.172	H-atom parameters constrained
S = 1.00	w = 1/[σ²(F_o²) + (0.0803P)²] where P = (F_o² + 2F_c²)/3
3422 reflections	(Δ/σ)_max < 0.001
231 parameters	Δρ_max = 0.15 e Å⁻³
0 restraints	Δρ_min = −0.21 e Å⁻³

Crystal data top

C₂₄H₂₆O	V = 1954.6 (15) Å³
M_r = 330.45	Z = 4
Monoclinic, P2₁/n	Mo Kα radiation
a = 8.014 (4) Å	µ = 0.07 mm⁻¹
b = 15.472 (7) Å	T = 296 K
c = 16.006 (7) Å	0.20 × 0.17 × 0.15 mm
β = 99.98 (2)°

Data collection top

Bruker APEXII CCD diffractometer	3422 independent reflections
Absorption correction: multi-scan (SADABS; Bruker, 2009)	1532 reflections with I > 2σ(I)
T_min = 0.987, T_max = 0.990	R_int = 0.138
17522 measured reflections

Refinement top

R[F² > 2σ(F²)] = 0.071	0 restraints
wR(F²) = 0.172	H-atom parameters constrained
S = 1.00	Δρ_max = 0.15 e Å⁻³
3422 reflections	Δρ_min = −0.21 e Å⁻³
231 parameters

Special details top

Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes.

Refinement. Refinement of F² against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F², conventional R-factors R are based on F, with F set to zero for negative F². The threshold expression of F² > σ(F²) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F² are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å²) top

	x	y	z	U_iso*/U_eq
O	−0.0324 (3)	0.35794 (17)	0.04276 (16)	0.0721 (8)
H0	−0.0789	0.3841	0.0769	0.108*
C3	0.3942 (4)	0.3867 (2)	0.1619 (2)	0.0473 (9)
H3	0.4591	0.4304	0.1914	0.057*
C2	0.2285 (4)	0.4048 (2)	0.1234 (2)	0.0436 (9)
C13	0.0376 (4)	0.4945 (2)	0.1985 (2)	0.0477 (9)
C1	0.1322 (4)	0.3377 (2)	0.0801 (2)	0.0459 (9)
C5	0.3647 (5)	0.2417 (2)	0.1124 (2)	0.0523 (10)
H5	0.4114	0.1871	0.1088	0.063*
C4	0.4652 (4)	0.3057 (2)	0.1578 (2)	0.0480 (9)
C6	0.1977 (4)	0.2555 (2)	0.0721 (2)	0.0473 (9)
C24	0.3685 (4)	0.5791 (2)	0.0708 (2)	0.0551 (10)
H24	0.3627	0.5374	0.0285	0.066*
C19	0.2722 (4)	0.5693 (2)	0.1352 (2)	0.0442 (9)
C12	0.1469 (4)	0.4931 (2)	0.1297 (2)	0.0449 (9)
H12	0.0684	0.5009	0.0761	0.054*
C21	0.3905 (5)	0.7026 (2)	0.1965 (3)	0.0645 (11)
H21	0.3976	0.7441	0.2389	0.077*
C23	0.4725 (5)	0.6503 (3)	0.0696 (3)	0.0688 (12)
H23	0.5354	0.6564	0.0263	0.083*
C20	0.2870 (4)	0.6314 (2)	0.1981 (2)	0.0535 (10)
H20	0.2263	0.6252	0.2422	0.064*
C14	−0.1169 (5)	0.5383 (2)	0.1838 (3)	0.0633 (11)
H14	−0.1529	0.5650	0.1317	0.076*
C7	0.0933 (5)	0.1835 (2)	0.0202 (2)	0.0565 (10)
C18	0.0871 (5)	0.4564 (2)	0.2772 (2)	0.0593 (10)
H18	0.1895	0.4267	0.2882	0.071*
C17	−0.0125 (6)	0.4612 (3)	0.3404 (3)	0.0739 (12)
H17	0.0227	0.4351	0.3928	0.089*
C22	0.4836 (5)	0.7122 (3)	0.1319 (3)	0.0708 (12)
H22	0.5530	0.7602	0.1306	0.085*
C8	−0.0686 (5)	0.1625 (2)	0.0564 (3)	0.0857 (14)
H8A	−0.0378	0.1443	0.1144	0.129*
H8B	−0.1298	0.1170	0.0238	0.129*
H8C	−0.1386	0.2131	0.0537	0.129*
C9	0.1948 (5)	0.0992 (2)	0.0221 (3)	0.0924 (15)
H9A	0.2963	0.1094	−0.0006	0.139*
H9B	0.1274	0.0562	−0.0115	0.139*
H9C	0.2240	0.0791	0.0795	0.139*
C15	−0.2170 (5)	0.5426 (3)	0.2458 (3)	0.0772 (13)
H15	−0.3209	0.5708	0.2347	0.093*
C16	−0.1636 (6)	0.5053 (3)	0.3238 (3)	0.0807 (14)
H16	−0.2302	0.5099	0.3657	0.097*
C10	0.0469 (6)	0.2111 (3)	−0.0734 (2)	0.0864 (14)
H10A	−0.0214	0.2624	−0.0775	0.130*
H10B	−0.0155	0.1655	−0.1056	0.130*
H10C	0.1485	0.2225	−0.0956	0.130*
C11	0.6475 (5)	0.2879 (2)	0.1987 (2)	0.0733 (12)
H11A	0.7193	0.2921	0.1567	0.110*
H11B	0.6558	0.2308	0.2227	0.110*
H11C	0.6828	0.3295	0.2427	0.110*

Atomic displacement parameters (Å²) top

	U¹¹	U²²	U³³	U¹²	U¹³	U²³
O	0.0540 (17)	0.071 (2)	0.086 (2)	0.0068 (14)	−0.0039 (15)	−0.0090 (16)
C3	0.049 (2)	0.048 (2)	0.044 (2)	0.0002 (18)	0.0064 (18)	−0.0042 (18)
C2	0.047 (2)	0.040 (2)	0.043 (2)	0.0048 (18)	0.0068 (17)	−0.0015 (18)
C13	0.044 (2)	0.037 (2)	0.064 (3)	−0.0031 (17)	0.014 (2)	0.0000 (19)
C1	0.047 (2)	0.043 (2)	0.047 (2)	0.0051 (19)	0.0068 (18)	0.0031 (19)
C5	0.071 (3)	0.037 (2)	0.052 (2)	0.009 (2)	0.021 (2)	0.0022 (19)
C4	0.051 (2)	0.048 (2)	0.046 (2)	0.013 (2)	0.0101 (18)	−0.0005 (19)
C6	0.060 (3)	0.041 (2)	0.044 (2)	0.0000 (19)	0.0153 (19)	−0.0031 (19)
C24	0.060 (2)	0.053 (3)	0.054 (2)	0.003 (2)	0.015 (2)	0.000 (2)
C19	0.043 (2)	0.040 (2)	0.047 (2)	0.0047 (17)	0.0011 (18)	0.0055 (19)
C12	0.049 (2)	0.038 (2)	0.047 (2)	0.0041 (17)	0.0030 (17)	0.0017 (17)
C21	0.068 (3)	0.048 (3)	0.077 (3)	−0.005 (2)	0.011 (2)	−0.005 (2)
C23	0.066 (3)	0.072 (3)	0.071 (3)	−0.013 (2)	0.021 (2)	0.019 (3)
C20	0.057 (2)	0.045 (2)	0.060 (2)	−0.0050 (19)	0.0153 (19)	−0.004 (2)
C14	0.055 (2)	0.051 (3)	0.086 (3)	0.003 (2)	0.019 (2)	0.003 (2)
C7	0.068 (3)	0.047 (3)	0.054 (3)	−0.007 (2)	0.013 (2)	−0.009 (2)
C18	0.063 (2)	0.055 (3)	0.062 (3)	0.006 (2)	0.019 (2)	0.008 (2)
C17	0.088 (3)	0.062 (3)	0.079 (3)	−0.004 (2)	0.036 (3)	0.005 (2)
C22	0.070 (3)	0.056 (3)	0.084 (3)	−0.012 (2)	0.009 (3)	0.009 (3)
C8	0.091 (3)	0.071 (3)	0.102 (3)	−0.032 (3)	0.037 (3)	−0.019 (3)
C9	0.108 (4)	0.047 (3)	0.121 (4)	−0.003 (3)	0.018 (3)	−0.027 (3)
C15	0.058 (3)	0.063 (3)	0.116 (4)	0.008 (2)	0.031 (3)	0.001 (3)
C16	0.083 (3)	0.059 (3)	0.112 (4)	0.001 (3)	0.050 (3)	−0.006 (3)
C10	0.104 (4)	0.089 (3)	0.063 (3)	−0.025 (3)	0.009 (3)	−0.018 (3)
C11	0.059 (3)	0.075 (3)	0.081 (3)	0.018 (2)	0.000 (2)	−0.002 (2)

Geometric parameters (Å, º) top

O—C1	1.386 (4)	C20—H20	0.9300
O—H0	0.8200	C14—C15	1.382 (5)
C3—C4	1.382 (4)	C14—H14	0.9300
C3—C2	1.392 (4)	C7—C9	1.535 (5)
C3—H3	0.9300	C7—C10	1.541 (5)
C2—C1	1.403 (4)	C7—C8	1.545 (5)
C2—C12	1.526 (4)	C18—C17	1.395 (5)
C13—C18	1.386 (4)	C18—H18	0.9300
C13—C14	1.395 (4)	C17—C16	1.375 (5)
C13—C12	1.521 (4)	C17—H17	0.9300
C1—C6	1.390 (4)	C22—H22	0.9300
C5—C6	1.398 (4)	C8—H8A	0.9600
C5—C4	1.398 (5)	C8—H8B	0.9600
C5—H5	0.9300	C8—H8C	0.9600
C4—C11	1.519 (5)	C9—H9A	0.9600
C6—C7	1.546 (5)	C9—H9B	0.9600
C24—C23	1.384 (5)	C9—H9C	0.9600
C24—C19	1.400 (4)	C15—C16	1.374 (5)
C24—H24	0.9300	C15—H15	0.9300
C19—C20	1.382 (4)	C16—H16	0.9300
C19—C12	1.540 (4)	C10—H10A	0.9600
C12—H12	0.9800	C10—H10B	0.9600
C21—C20	1.381 (5)	C10—H10C	0.9600
C21—C22	1.384 (5)	C11—H11A	0.9600
C21—H21	0.9300	C11—H11B	0.9600
C23—C22	1.373 (5)	C11—H11C	0.9600
C23—H23	0.9300

C1—O—H0	109.5	C9—C7—C10	107.0 (3)
C4—C3—C2	122.0 (3)	C9—C7—C8	106.9 (3)
C4—C3—H3	119.0	C10—C7—C8	110.3 (3)
C2—C3—H3	119.0	C9—C7—C6	111.5 (3)
C3—C2—C1	118.1 (3)	C10—C7—C6	109.9 (3)
C3—C2—C12	122.5 (3)	C8—C7—C6	111.2 (3)
C1—C2—C12	119.3 (3)	C13—C18—C17	121.8 (4)
C18—C13—C14	117.8 (3)	C13—C18—H18	119.1
C18—C13—C12	122.8 (3)	C17—C18—H18	119.1
C14—C13—C12	119.4 (3)	C16—C17—C18	118.8 (4)
O—C1—C6	120.9 (3)	C16—C17—H17	120.6
O—C1—C2	116.5 (3)	C18—C17—H17	120.6
C6—C1—C2	122.6 (3)	C23—C22—C21	119.4 (4)
C6—C5—C4	123.4 (3)	C23—C22—H22	120.3
C6—C5—H5	118.3	C21—C22—H22	120.3
C4—C5—H5	118.3	C7—C8—H8A	109.5
C3—C4—C5	117.5 (3)	C7—C8—H8B	109.5
C3—C4—C11	121.1 (3)	H8A—C8—H8B	109.5
C5—C4—C11	121.3 (3)	C7—C8—H8C	109.5
C1—C6—C5	116.4 (3)	H8A—C8—H8C	109.5
C1—C6—C7	122.1 (3)	H8B—C8—H8C	109.5
C5—C6—C7	121.6 (3)	C7—C9—H9A	109.5
C23—C24—C19	120.4 (4)	C7—C9—H9B	109.5
C23—C24—H24	119.8	H9A—C9—H9B	109.5
C19—C24—H24	119.8	C7—C9—H9C	109.5
C20—C19—C24	118.2 (3)	H9A—C9—H9C	109.5
C20—C19—C12	123.2 (3)	H9B—C9—H9C	109.5
C24—C19—C12	118.5 (3)	C16—C15—C14	120.3 (4)
C13—C12—C2	111.6 (3)	C16—C15—H15	119.8
C13—C12—C19	113.5 (3)	C14—C15—H15	119.8
C2—C12—C19	114.0 (3)	C15—C16—C17	120.6 (4)
C13—C12—H12	105.6	C15—C16—H16	119.7
C2—C12—H12	105.6	C17—C16—H16	119.7
C19—C12—H12	105.6	C7—C10—H10A	109.5
C20—C21—C22	120.2 (4)	C7—C10—H10B	109.5
C20—C21—H21	119.9	H10A—C10—H10B	109.5
C22—C21—H21	119.9	C7—C10—H10C	109.5
C22—C23—C24	120.6 (4)	H10A—C10—H10C	109.5
C22—C23—H23	119.7	H10B—C10—H10C	109.5
C24—C23—H23	119.7	C4—C11—H11A	109.5
C21—C20—C19	121.2 (4)	C4—C11—H11B	109.5
C21—C20—H20	119.4	H11A—C11—H11B	109.5
C19—C20—H20	119.4	C4—C11—H11C	109.5
C15—C14—C13	120.7 (4)	H11A—C11—H11C	109.5
C15—C14—H14	119.6	H11B—C11—H11C	109.5
C13—C14—H14	119.6

Hydrogen-bond geometry (Å, º) top

D—H···A	D—H	H···A	D···A	D—H···A
C8—H8C···O	0.96	2.41	3.049 (4)	123
C10—H10A···O	0.96	2.44	3.071 (5)	123
C12—H12···O	0.98	2.38	2.771 (4)	103

Experimental details

Crystal data
Chemical formula	C₂₄H₂₆O
M_r	330.45
Crystal system, space group	Monoclinic, P2₁/n
Temperature (K)	296
a, b, c (Å)	8.014 (4), 15.472 (7), 16.006 (7)
β (°)	99.98 (2)
V (Å³)	1954.6 (15)
Z	4
Radiation type	Mo Kα
µ (mm⁻¹)	0.07
Crystal size (mm)	0.20 × 0.17 × 0.15

Data collection
Diffractometer	Bruker APEXII CCD diffractometer
Absorption correction	Multi-scan (SADABS; Bruker, 2009)
T_min, T_max	0.987, 0.990
No. of measured, independent and observed [I > 2σ(I)] reflections	17522, 3422, 1532
R_int	0.138
(sin θ/λ)_max (Å⁻¹)	0.594

Refinement
R[F² > 2σ(F²)], wR(F²), S	0.071, 0.172, 1.00
No. of reflections	3422
No. of parameters	231
H-atom treatment	H-atom parameters constrained
Δρ_max, Δρ_min (e Å⁻³)	0.15, −0.21

Computer programs: APEX2 (Bruker, 2009), SAINT (Bruker, 2009), SHELXS97 (Sheldrick, 2008), SHELXL97 (Sheldrick, 2008), SHELXTL (Sheldrick, 2008).

Hydrogen-bond geometry (Å, º) top

D—H···A	D—H	H···A	D···A	D—H···A
C8—H8C···O	0.9597	2.4142	3.049 (4)	123.35
C10—H10A···O	0.9599	2.4407	3.071 (5)	123.02
C12—H12···O	0.9794	2.3833	2.771 (4)	102.89

Acknowledgements

YK gratefully acknowledges financial support from the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (No. 2010–0007092).

References

Bruker (2009). SMART, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA. Google Scholar
Kim, S. H., Yoon, S., Mun, S.-D., Lee, H.-H., Lee, J. & Kim, Y. (2012). Polyhedron, 31, 665–670. Web of Science CSD CrossRef CAS Google Scholar
Sheldrick, G. M. (2008). Acta Cryst. A64, 112–122. Web of Science CrossRef CAS IUCr Journals Google Scholar