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Figure 1 Preparation of N-[(methyl 5-deoxy-2,3-O-isopropylidene-β-D-ribofuranoside)-5-yl]-N,N,N-trimethylammonium tosylate, (4). Reagents: (i) SnCl2·2H2O, conc. H2SO4, acetone, MeOH; (ii) TsCl, py; (iii) 33% ethanolic solution of NMe3. |
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