organic compounds
4,6-Di-tert-butyl-2,3-dihydroxybenzaldehyde
aLaboratory of Free Radical Polymerization, G.A. Razuvaev Institute of Organometallic Chemistry of the Russian Academy of Science, Tropinina str, 49, Nizhny Novgorod, 603950, Russian Federation, bGroup of X-Ray Diffraction Investigations, G.A. Razuvaev Institute of Organometallic Chemistry of the Russian Academy of Science, Tropinina str, 49, Nizhny Novgorod, 603950, Russian Federation, and cLaboratory of the Chemistry of Organometallic Compounds, G.A. Razuvaev Institute of Organometallic Chemistry of the Russian Academy of Science, Tropinina str, 49, Nizhny Novgorod, 603950, Russian Federation
*Correspondence e-mail: mars@iomc.ras.ru
The title compound, C15H22O3, crystallizes with two independent molecules in the In each molecule, one hydroxy group (at position 2) is involved in an intramolecular O—H⋯O hydrogen bond, and another one (at position 3) exhibits bifurcated hydrogen-bonding being involved in intra- and intermolecular O—H⋯O interactions. In the crystal, O—H⋯O hydrogen bonds link alternating independent molecules into chains running along [010].
CCDC reference: 948325
Related literature
For the ). For applications of Shiff base ligands based on 2,3-dihydroxybenzaldehyde, see: Albrecht et al. (2004); Furutachi et al. (2010); Belmonte et al. (2012).
of 2,3-dihydroxybenzaldehyde, see: Ng (2005Experimental
Crystal data
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Data collection: SMART (Bruker, 2008); cell SAINT (Bruker, 2008); data reduction: SAINT; program(s) used to solve structure: SHELXTL (Sheldrick, 2008); program(s) used to refine structure: SHELXTL; molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL.
Supporting information
CCDC reference: 948325
10.1107/S1600536813025488/cv5427sup1.cif
contains datablocks global, I. DOI:Structure factors: contains datablock I. DOI: 10.1107/S1600536813025488/cv5427Isup2.hkl
Supporting information file. DOI: 10.1107/S1600536813025488/cv5427Isup3.cml
4,6-Di-tert-butyl-2,3-dihydroxybenzaldehyde was synthesized by following scheme (Fig. 2).
1,2-Bis(benzyloxy)-3,5-di-tert-butylbenzene (1). Mixture of 3,5-di-tert-butyl-catechol (22.2 g, 0.1 mol), benzyl chloride (23.0 ml, 0.2 mol) and K2CO3 (27.6 g, 0.2 mol) in DMF (100 ml) was heated at 90°C for 24 h under argon atmosphere. After cooling, water (300 ml) was added to reaction mixture and the product was extracted by hexane (3*200 ml). Extract was dried by Na2SO4. The solvent was evaporated and the product was dried under vacuum. The yield was 39.4 g (98%). m.p.=86-87°C dH (200 MHz CDCl3) 7.48-7.28 (m, 10H, 2Ph), 7.02 (d, 1H, Car-H, JHH=2.2 Hz), 6.95 (d, 1H, Car-H, JHH=2.2 Hz), 5.16 (s, 2H, CH2Ph), 5.11 (s, 2H, CH2Ph), 1.43 and 1.32 (s, both 9H, t-Bu). dC (50 MHz CDCl3) 151.85, 145.71, 145.46, 142.73, 138.57, 137.33, 128.45, 128.22, 127.83, 127.79, 127.58, 127.33, 116.55, 110.78, 73.50, 71.44, 35.48, 34.80, 31.56, 30.87.
2,3-bis(benzyloxy)-4,6-di-tert-butylbenzaldehyde (2). The compound 1 (20.1 g, 0.05 mol) was dissolved in THF (200 ml), and the solution was cooled to -78°C. TMEDA (7.5 ml, 0.05 mol) and BuLi in hexane (160 ml 0.6 M, 0.1 mol) were added to the mixture. It was stirred for 3 h and DMF (7.7 ml, 0.1 mol) was added. Mixture was stirred at -78°C for 3 h and then was warmed to room temperature, and stirring was continued overnight. The resulting mixture was diluted by water (300 ml) and neutralized by conc. HCl. The mixture of 1 and 2 was extracted by hexane (3*200 ml). The solvent was evaporated and the crude product was purified by
on silica gel (eluent hexane:ethyl acetate 40:1, second fraction). The yield was 15.3 g (71%). m.p.=84-85°C. dH (200 MHz CDCl3) 10.53 (s, 1H, CHO), 7.51-7.31 (m, 11H, 2Ph and Car-H), 5.21 (s, 2H, CH2Ph), 4.98 (s, 2H, CH2Ph), 1.45 and 1.36 (s, both 9H, t-Bu). dC (50 MHz CDCl3) 196.65, 151.76, 149.07, 146.09, 144.31, 137.89, 136.49, 132.26, 128.88, 128.41, 128.36,128.22, 127.56, 127.16, 120.83, 75.85, 73.69, 36.13, 35.86, 32.02, 30.53.4,6-Di-tert-butyl-2,3-dihydroxybenzaldehyde (3). 0.1 M solution of BCl3 in CH2Cl2 (60 ml) was added with cooling (0°C) to 2 (12.9 g, 0.03 mol) in CH2Cl2 (30 ml). Reaction mixture was stirred for 24 h. Water (50 ml) was added to the mixture, and stirring was continued for 24 h. Product was extracted by CH2Cl2 and washed by water (4*50 ml). Extract was dried by Na2SO4 and the solvent was evaporated. 3 was recrystallized from methanol (50 ml). Yellow crystalline (6.4 g, 85%). m.p.=115-116°C. nmax (nujol) 3620.86 (nar.), 3529-3240 (br.), 1624 (C=O)cm-1. dH (200 MHz CDCl3) 12.92 (s, 1H, OH), 10.71 (s, 1H, CHO), 6.88 (s, 1H, Car-H), 5.99 (s, 1H, OH), 1.42 and 1.49 (s, both 9H, t-Bu). dC (50 MHz CDCl3) 196.58, 151.93, 143.24, 141.77, 141.73, 115.99 (C-H), 115.19, 35.75, 35.72, 33.76, 29.00. Anal. Calcd for C15H22O3: C 71.97, H 8.86. Found: C 71.89, H 8.90.
C-bound H atoms, excluding H7A and H7B, were placed in calculated positions and were refined in the riding model. The rest H atoms were located on a difference map and were refined isotropically.
Data collection: SMART (Bruker, 2008); cell
SAINT (Bruker, 2008); data reduction: SAINT (Bruker, 2008); program(s) used to solve structure: SHELXTL (Sheldrick, 2008); program(s) used to refine structure: SHELXTL (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXTL (Sheldrick, 2008).Fig. 1. Two independent molecules of the title compound showing the atomic numering and 30% probability displacement ellipsoids. Dashed lines denote hydrogen bonds. C-bound H atoms omitted for clarity. | |
Fig. 2. Synthesis of sterically hindered salicylic aldehyde 3. Reagents and conditions: a) benzyl chloride (BnCl), K2CO3, DMF (98%); b) butyllithium (BuLi) in hexane, tetramethylethylenediamine (TMEDA); DMF; H2O (71%); c) BCl3 in CH2Cl2; H2O (85%). |
C15H22O3 | Z = 4 |
Mr = 250.33 | F(000) = 544 |
Triclinic, P1 | Dx = 1.131 Mg m−3 |
Hall symbol: -P 1 | Melting point: 115 K |
a = 9.3113 (9) Å | Mo Kα radiation, λ = 0.71073 Å |
b = 10.6511 (10) Å | Cell parameters from 900 reflections |
c = 15.3962 (15) Å | θ = 2–30° |
α = 95.242 (2)° | µ = 0.08 mm−1 |
β = 103.085 (2)° | T = 100 K |
γ = 95.492 (2)° | Prism, yellow |
V = 1470.4 (2) Å3 | 0.70 × 0.16 × 0.16 mm |
Bruker SMART APEX CCD area-detector diffractometer | 5740 independent reflections |
Radiation source: fine-focus sealed tube | 4411 reflections with I > 2σ(I) |
Graphite monochromator | Rint = 0.018 |
ω scans | θmax = 26.0°, θmin = 2.2° |
Absorption correction: multi-scan (SADABS; Sheldrick, 2008) | h = −11→11 |
Tmin = 0.948, Tmax = 0.988 | k = −11→13 |
8903 measured reflections | l = −18→18 |
Refinement on F2 | 0 restraints |
Least-squares matrix: full | H atoms treated by a mixture of independent and constrained refinement |
R[F2 > 2σ(F2)] = 0.046 | w = 1/[σ2(Fo2) + (0.0779P)2 + 0.0742P] where P = (Fo2 + 2Fc2)/3 |
wR(F2) = 0.130 | (Δ/σ)max < 0.001 |
S = 1.06 | Δρmax = 0.25 e Å−3 |
5740 reflections | Δρmin = −0.21 e Å−3 |
361 parameters |
C15H22O3 | γ = 95.492 (2)° |
Mr = 250.33 | V = 1470.4 (2) Å3 |
Triclinic, P1 | Z = 4 |
a = 9.3113 (9) Å | Mo Kα radiation |
b = 10.6511 (10) Å | µ = 0.08 mm−1 |
c = 15.3962 (15) Å | T = 100 K |
α = 95.242 (2)° | 0.70 × 0.16 × 0.16 mm |
β = 103.085 (2)° |
Bruker SMART APEX CCD area-detector diffractometer | 5740 independent reflections |
Absorption correction: multi-scan (SADABS; Sheldrick, 2008) | 4411 reflections with I > 2σ(I) |
Tmin = 0.948, Tmax = 0.988 | Rint = 0.018 |
8903 measured reflections |
R[F2 > 2σ(F2)] = 0.046 | 0 restraints |
wR(F2) = 0.130 | H atoms treated by a mixture of independent and constrained refinement |
S = 1.06 | Δρmax = 0.25 e Å−3 |
5740 reflections | Δρmin = −0.21 e Å−3 |
361 parameters |
Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes. |
Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger. |
x | y | z | Uiso*/Ueq | ||
O1A | 0.13058 (9) | −0.38259 (6) | 0.24551 (5) | 0.0316 (2) | |
H1A | 0.1319 (16) | −0.3993 (13) | 0.1884 (10) | 0.054 (4)* | |
O2A | 0.14084 (8) | −0.22900 (6) | 0.12158 (5) | 0.02752 (18) | |
H2A | 0.1392 (16) | −0.1505 (13) | 0.0745 (10) | 0.057 (4)* | |
O3A | 0.15955 (9) | −0.01066 (7) | 0.07434 (5) | 0.02887 (19) | |
C1A | 0.15563 (11) | −0.25515 (9) | 0.27164 (7) | 0.0226 (2) | |
C2A | 0.16112 (11) | −0.17213 (9) | 0.20646 (7) | 0.0216 (2) | |
C3A | 0.18605 (10) | −0.03905 (9) | 0.22842 (7) | 0.0214 (2) | |
C4A | 0.21238 (11) | 0.01227 (9) | 0.32024 (7) | 0.0223 (2) | |
C5A | 0.20502 (11) | −0.07376 (9) | 0.38215 (7) | 0.0229 (2) | |
H5AA | 0.2218 | −0.0407 | 0.4435 | 0.027* | |
C6A | 0.17450 (11) | −0.20648 (9) | 0.36057 (7) | 0.0232 (2) | |
C7A | 0.18009 (12) | 0.03568 (9) | 0.15347 (7) | 0.0253 (2) | |
H7A | 0.1889 (13) | 0.1306 (11) | 0.1631 (8) | 0.031 (3)* | |
C8A | 0.24859 (12) | 0.15602 (9) | 0.35317 (7) | 0.0261 (3) | |
C9A | 0.28235 (14) | 0.18201 (10) | 0.45588 (8) | 0.0352 (3) | |
H9AA | 0.1952 | 0.1507 | 0.4768 | 0.053* | |
H9AB | 0.3066 | 0.2736 | 0.4741 | 0.053* | |
H9AC | 0.3668 | 0.1383 | 0.4823 | 0.053* | |
C10A | 0.11678 (13) | 0.22788 (10) | 0.31648 (8) | 0.0337 (3) | |
H10A | 0.0299 | 0.1942 | 0.3368 | 0.051* | |
H10B | 0.0940 | 0.2169 | 0.2507 | 0.051* | |
H10C | 0.1423 | 0.3184 | 0.3385 | 0.051* | |
C11A | 0.38925 (13) | 0.21161 (10) | 0.32590 (8) | 0.0331 (3) | |
H11A | 0.3704 | 0.2048 | 0.2603 | 0.050* | |
H11B | 0.4719 | 0.1641 | 0.3493 | 0.050* | |
H11C | 0.4146 | 0.3011 | 0.3508 | 0.050* | |
C12A | 0.15986 (13) | −0.29441 (10) | 0.43265 (7) | 0.0295 (3) | |
C13A | 0.17984 (15) | −0.22047 (11) | 0.52559 (8) | 0.0369 (3) | |
H13A | 0.1043 | −0.1620 | 0.5233 | 0.055* | |
H13B | 0.2789 | −0.1721 | 0.5437 | 0.055* | |
H13C | 0.1691 | −0.2801 | 0.5692 | 0.055* | |
C14A | 0.00288 (14) | −0.36849 (11) | 0.40655 (8) | 0.0382 (3) | |
H14A | −0.0111 | −0.4201 | 0.3485 | 0.057* | |
H14B | −0.0713 | −0.3086 | 0.4020 | 0.057* | |
H14C | −0.0088 | −0.4240 | 0.4525 | 0.057* | |
C15A | 0.27806 (14) | −0.38673 (11) | 0.43956 (8) | 0.0387 (3) | |
H15A | 0.2660 | −0.4369 | 0.3812 | 0.058* | |
H15B | 0.2664 | −0.4437 | 0.4846 | 0.058* | |
H15C | 0.3772 | −0.3385 | 0.4573 | 0.058* | |
O1B | 0.19869 (9) | 0.08055 (6) | −0.08108 (5) | 0.02929 (19) | |
H1B | 0.1807 (18) | 0.0734 (14) | −0.0277 (11) | 0.067 (5)* | |
O2B | 0.14124 (8) | 0.25992 (6) | 0.03230 (5) | 0.02881 (18) | |
H2B | 0.1334 (19) | 0.3373 (15) | 0.0690 (11) | 0.075 (5)* | |
O3B | 0.14462 (10) | 0.48947 (7) | 0.08636 (5) | 0.0382 (2) | |
C1B | 0.22899 (11) | 0.20423 (9) | −0.09443 (7) | 0.0229 (2) | |
C2B | 0.19582 (11) | 0.30029 (9) | −0.03624 (7) | 0.0227 (2) | |
C3B | 0.22243 (11) | 0.42972 (9) | −0.04678 (7) | 0.0242 (2) | |
C4B | 0.28051 (11) | 0.46447 (9) | −0.12054 (7) | 0.0241 (2) | |
C5B | 0.31494 (11) | 0.36661 (9) | −0.17478 (7) | 0.0247 (2) | |
H5BA | 0.3557 | 0.3885 | −0.2234 | 0.030* | |
C6B | 0.29418 (11) | 0.23659 (9) | −0.16335 (7) | 0.0230 (2) | |
C7B | 0.19374 (14) | 0.51970 (10) | 0.02154 (8) | 0.0338 (3) | |
H7B | 0.2122 (16) | 0.6105 (13) | 0.0160 (10) | 0.055 (4)* | |
C8B | 0.30439 (12) | 0.60314 (10) | −0.14183 (8) | 0.0302 (3) | |
C9B | 0.43000 (15) | 0.68113 (11) | −0.06932 (10) | 0.0469 (4) | |
H9BA | 0.4426 | 0.7687 | −0.0837 | 0.070* | |
H9BB | 0.5226 | 0.6436 | −0.0671 | 0.070* | |
H9BC | 0.4049 | 0.6809 | −0.0108 | 0.070* | |
C10B | 0.16044 (14) | 0.66445 (11) | −0.15304 (9) | 0.0418 (3) | |
H10D | 0.1763 | 0.7494 | −0.1714 | 0.063* | |
H10E | 0.1305 | 0.6712 | −0.0959 | 0.063* | |
H10F | 0.0821 | 0.6121 | −0.1991 | 0.063* | |
C11B | 0.34989 (16) | 0.60891 (11) | −0.23132 (9) | 0.0459 (4) | |
H11D | 0.3606 | 0.6974 | −0.2441 | 0.069* | |
H11E | 0.2734 | 0.5587 | −0.2796 | 0.069* | |
H11F | 0.4447 | 0.5743 | −0.2274 | 0.069* | |
C12B | 0.34396 (12) | 0.13435 (10) | −0.22352 (7) | 0.0279 (3) | |
C13B | 0.42121 (14) | 0.19175 (11) | −0.29129 (8) | 0.0379 (3) | |
H13D | 0.3519 | 0.2374 | −0.3309 | 0.057* | |
H13E | 0.4530 | 0.1237 | −0.3272 | 0.057* | |
H13F | 0.5081 | 0.2508 | −0.2591 | 0.057* | |
C14B | 0.20742 (14) | 0.04340 (11) | −0.27618 (8) | 0.0378 (3) | |
H14D | 0.1382 | 0.0911 | −0.3141 | 0.057* | |
H14E | 0.1581 | 0.0036 | −0.2340 | 0.057* | |
H14F | 0.2390 | −0.0225 | −0.3140 | 0.057* | |
C15B | 0.45488 (13) | 0.06066 (11) | −0.16510 (8) | 0.0358 (3) | |
H15D | 0.5414 | 0.1194 | −0.1319 | 0.054* | |
H15E | 0.4869 | −0.0042 | −0.2035 | 0.054* | |
H15F | 0.4072 | 0.0198 | −0.1226 | 0.054* |
U11 | U22 | U33 | U12 | U13 | U23 | |
O1A | 0.0487 (5) | 0.0195 (3) | 0.0268 (4) | −0.0008 (3) | 0.0121 (4) | 0.0013 (3) |
O2A | 0.0381 (4) | 0.0244 (3) | 0.0206 (4) | 0.0004 (3) | 0.0105 (3) | 0.0001 (3) |
O3A | 0.0371 (4) | 0.0276 (3) | 0.0233 (4) | 0.0024 (3) | 0.0099 (3) | 0.0047 (3) |
C1A | 0.0237 (5) | 0.0197 (4) | 0.0254 (5) | 0.0007 (4) | 0.0085 (4) | 0.0027 (4) |
C2A | 0.0216 (5) | 0.0247 (5) | 0.0187 (5) | 0.0008 (4) | 0.0069 (4) | 0.0005 (4) |
C3A | 0.0190 (5) | 0.0214 (4) | 0.0257 (5) | 0.0020 (4) | 0.0087 (4) | 0.0043 (4) |
C4A | 0.0184 (5) | 0.0233 (5) | 0.0257 (5) | 0.0028 (4) | 0.0065 (4) | 0.0019 (4) |
C5A | 0.0233 (5) | 0.0252 (5) | 0.0205 (5) | 0.0017 (4) | 0.0072 (4) | 0.0006 (4) |
C6A | 0.0209 (5) | 0.0254 (5) | 0.0240 (5) | 0.0018 (4) | 0.0063 (4) | 0.0043 (4) |
C7A | 0.0260 (5) | 0.0254 (5) | 0.0259 (5) | 0.0023 (4) | 0.0090 (4) | 0.0037 (4) |
C8A | 0.0289 (5) | 0.0225 (5) | 0.0268 (5) | −0.0012 (4) | 0.0099 (4) | −0.0006 (4) |
C9A | 0.0444 (7) | 0.0274 (5) | 0.0314 (6) | −0.0031 (5) | 0.0101 (5) | −0.0043 (4) |
C10A | 0.0368 (6) | 0.0237 (5) | 0.0414 (7) | 0.0052 (4) | 0.0120 (5) | 0.0000 (4) |
C11A | 0.0320 (6) | 0.0298 (5) | 0.0362 (6) | −0.0049 (4) | 0.0105 (5) | 0.0007 (4) |
C12A | 0.0351 (6) | 0.0289 (5) | 0.0250 (6) | 0.0017 (4) | 0.0075 (5) | 0.0077 (4) |
C13A | 0.0491 (7) | 0.0382 (6) | 0.0252 (6) | 0.0048 (5) | 0.0107 (5) | 0.0093 (5) |
C14A | 0.0422 (7) | 0.0395 (6) | 0.0353 (6) | −0.0043 (5) | 0.0141 (5) | 0.0136 (5) |
C15A | 0.0484 (7) | 0.0333 (6) | 0.0345 (6) | 0.0091 (5) | 0.0054 (6) | 0.0118 (5) |
O1B | 0.0419 (4) | 0.0208 (3) | 0.0293 (4) | 0.0014 (3) | 0.0179 (3) | 0.0031 (3) |
O2B | 0.0417 (4) | 0.0246 (3) | 0.0253 (4) | 0.0046 (3) | 0.0177 (3) | 0.0045 (3) |
O3B | 0.0614 (5) | 0.0276 (4) | 0.0314 (4) | 0.0090 (3) | 0.0219 (4) | 0.0026 (3) |
C1B | 0.0244 (5) | 0.0206 (4) | 0.0237 (5) | 0.0012 (4) | 0.0058 (4) | 0.0041 (4) |
C2B | 0.0243 (5) | 0.0258 (5) | 0.0190 (5) | 0.0016 (4) | 0.0071 (4) | 0.0051 (4) |
C3B | 0.0247 (5) | 0.0235 (5) | 0.0245 (5) | 0.0042 (4) | 0.0045 (4) | 0.0054 (4) |
C4B | 0.0201 (5) | 0.0261 (5) | 0.0254 (5) | 0.0001 (4) | 0.0036 (4) | 0.0072 (4) |
C5B | 0.0208 (5) | 0.0309 (5) | 0.0235 (5) | 0.0007 (4) | 0.0067 (4) | 0.0078 (4) |
C6B | 0.0195 (5) | 0.0286 (5) | 0.0202 (5) | 0.0014 (4) | 0.0046 (4) | 0.0012 (4) |
C7B | 0.0471 (7) | 0.0253 (5) | 0.0318 (6) | 0.0068 (5) | 0.0135 (5) | 0.0054 (4) |
C8B | 0.0290 (5) | 0.0257 (5) | 0.0361 (6) | −0.0009 (4) | 0.0069 (5) | 0.0114 (4) |
C9B | 0.0423 (7) | 0.0293 (6) | 0.0591 (9) | −0.0062 (5) | −0.0059 (7) | 0.0095 (6) |
C10B | 0.0364 (6) | 0.0305 (5) | 0.0613 (8) | 0.0034 (5) | 0.0112 (6) | 0.0217 (5) |
C11B | 0.0562 (8) | 0.0345 (6) | 0.0534 (8) | −0.0021 (5) | 0.0235 (6) | 0.0196 (5) |
C12B | 0.0287 (5) | 0.0322 (5) | 0.0250 (5) | 0.0032 (4) | 0.0122 (4) | −0.0003 (4) |
C13B | 0.0427 (6) | 0.0439 (6) | 0.0335 (6) | 0.0085 (5) | 0.0210 (5) | 0.0043 (5) |
C14B | 0.0378 (6) | 0.0408 (6) | 0.0322 (6) | −0.0012 (5) | 0.0112 (5) | −0.0107 (5) |
C15B | 0.0373 (6) | 0.0364 (6) | 0.0377 (6) | 0.0109 (5) | 0.0159 (5) | 0.0013 (5) |
O1A—C1A | 1.3623 (11) | O1B—C1B | 1.3645 (12) |
O1A—H1A | 0.885 (15) | O1B—H1B | 0.883 (17) |
O2A—C2A | 1.3535 (12) | O2B—C2B | 1.3567 (13) |
O2A—H2A | 1.154 (14) | O2B—H2B | 0.974 (17) |
O3A—C7A | 1.2373 (13) | O3B—C7B | 1.2436 (15) |
C1A—C6A | 1.3849 (15) | C1B—C6B | 1.3899 (15) |
C1A—C2A | 1.4030 (14) | C1B—C2B | 1.4011 (15) |
C2A—C3A | 1.4112 (13) | C2B—C3B | 1.4078 (14) |
C3A—C4A | 1.4260 (14) | C3B—C4B | 1.4269 (15) |
C3A—C7A | 1.4545 (15) | C3B—C7B | 1.4450 (16) |
C4A—C5A | 1.3893 (14) | C4B—C5B | 1.3830 (15) |
C4A—C8A | 1.5483 (13) | C4B—C8B | 1.5482 (14) |
C5A—C6A | 1.4086 (13) | C5B—C6B | 1.4124 (14) |
C5A—H5AA | 0.9500 | C5B—H5BA | 0.9500 |
C6A—C12A | 1.5366 (15) | C6B—C12B | 1.5380 (15) |
C7A—H7A | 1.001 (11) | C7B—H7B | 0.981 (14) |
C8A—C9A | 1.5345 (16) | C8B—C10B | 1.5284 (17) |
C8A—C10A | 1.5349 (16) | C8B—C11B | 1.5350 (19) |
C8A—C11A | 1.5454 (16) | C8B—C9B | 1.5355 (16) |
C9A—H9AA | 0.9800 | C9B—H9BA | 0.9800 |
C9A—H9AB | 0.9800 | C9B—H9BB | 0.9800 |
C9A—H9AC | 0.9800 | C9B—H9BC | 0.9800 |
C10A—H10A | 0.9800 | C10B—H10D | 0.9800 |
C10A—H10B | 0.9800 | C10B—H10E | 0.9800 |
C10A—H10C | 0.9800 | C10B—H10F | 0.9800 |
C11A—H11A | 0.9800 | C11B—H11D | 0.9800 |
C11A—H11B | 0.9800 | C11B—H11E | 0.9800 |
C11A—H11C | 0.9800 | C11B—H11F | 0.9800 |
C12A—C13A | 1.5323 (16) | C12B—C13B | 1.5335 (17) |
C12A—C15A | 1.5372 (17) | C12B—C15B | 1.5347 (16) |
C12A—C14A | 1.5414 (16) | C12B—C14B | 1.5382 (15) |
C13A—H13A | 0.9800 | C13B—H13D | 0.9800 |
C13A—H13B | 0.9800 | C13B—H13E | 0.9800 |
C13A—H13C | 0.9800 | C13B—H13F | 0.9800 |
C14A—H14A | 0.9800 | C14B—H14D | 0.9800 |
C14A—H14B | 0.9800 | C14B—H14E | 0.9800 |
C14A—H14C | 0.9800 | C14B—H14F | 0.9800 |
C15A—H15A | 0.9800 | C15B—H15D | 0.9800 |
C15A—H15B | 0.9800 | C15B—H15E | 0.9800 |
C15A—H15C | 0.9800 | C15B—H15F | 0.9800 |
C1A—O1A—H1A | 110.9 (9) | C1B—O1B—H1B | 112.1 (10) |
C2A—O2A—H2A | 107.9 (7) | C2B—O2B—H2B | 105.0 (10) |
O1A—C1A—C6A | 121.43 (9) | O1B—C1B—C6B | 121.39 (9) |
O1A—C1A—C2A | 118.85 (9) | O1B—C1B—C2B | 119.02 (10) |
C6A—C1A—C2A | 119.71 (9) | C6B—C1B—C2B | 119.58 (9) |
O2A—C2A—C1A | 115.16 (8) | O2B—C2B—C1B | 115.32 (9) |
O2A—C2A—C3A | 122.78 (9) | O2B—C2B—C3B | 122.63 (9) |
C1A—C2A—C3A | 122.06 (9) | C1B—C2B—C3B | 122.02 (10) |
C2A—C3A—C4A | 118.86 (9) | C2B—C3B—C4B | 119.22 (9) |
C2A—C3A—C7A | 116.16 (9) | C2B—C3B—C7B | 116.57 (10) |
C4A—C3A—C7A | 124.98 (9) | C4B—C3B—C7B | 124.17 (9) |
C5A—C4A—C3A | 116.85 (9) | C5B—C4B—C3B | 116.59 (9) |
C5A—C4A—C8A | 119.49 (9) | C5B—C4B—C8B | 119.99 (10) |
C3A—C4A—C8A | 123.65 (9) | C3B—C4B—C8B | 123.41 (9) |
C4A—C5A—C6A | 124.74 (9) | C4B—C5B—C6B | 124.97 (10) |
C4A—C5A—H5AA | 117.6 | C4B—C5B—H5BA | 117.5 |
C6A—C5A—H5AA | 117.6 | C6B—C5B—H5BA | 117.5 |
C1A—C6A—C5A | 117.68 (9) | C1B—C6B—C5B | 117.45 (9) |
C1A—C6A—C12A | 120.97 (9) | C1B—C6B—C12B | 120.95 (9) |
C5A—C6A—C12A | 121.34 (9) | C5B—C6B—C12B | 121.59 (10) |
O3A—C7A—C3A | 124.01 (9) | O3B—C7B—C3B | 124.19 (10) |
O3A—C7A—H7A | 115.1 (7) | O3B—C7B—H7B | 117.6 (9) |
C3A—C7A—H7A | 120.8 (7) | C3B—C7B—H7B | 118.2 (9) |
C9A—C8A—C10A | 106.64 (9) | C10B—C8B—C11B | 105.50 (10) |
C9A—C8A—C11A | 106.03 (9) | C10B—C8B—C9B | 111.32 (10) |
C10A—C8A—C11A | 110.55 (9) | C11B—C8B—C9B | 106.67 (10) |
C9A—C8A—C4A | 111.89 (9) | C10B—C8B—C4B | 111.07 (9) |
C10A—C8A—C4A | 111.07 (8) | C11B—C8B—C4B | 111.32 (9) |
C11A—C8A—C4A | 110.48 (9) | C9B—C8B—C4B | 110.77 (9) |
C8A—C9A—H9AA | 109.5 | C8B—C9B—H9BA | 109.5 |
C8A—C9A—H9AB | 109.5 | C8B—C9B—H9BB | 109.5 |
H9AA—C9A—H9AB | 109.5 | H9BA—C9B—H9BB | 109.5 |
C8A—C9A—H9AC | 109.5 | C8B—C9B—H9BC | 109.5 |
H9AA—C9A—H9AC | 109.5 | H9BA—C9B—H9BC | 109.5 |
H9AB—C9A—H9AC | 109.5 | H9BB—C9B—H9BC | 109.5 |
C8A—C10A—H10A | 109.5 | C8B—C10B—H10D | 109.5 |
C8A—C10A—H10B | 109.5 | C8B—C10B—H10E | 109.5 |
H10A—C10A—H10B | 109.5 | H10D—C10B—H10E | 109.5 |
C8A—C10A—H10C | 109.5 | C8B—C10B—H10F | 109.5 |
H10A—C10A—H10C | 109.5 | H10D—C10B—H10F | 109.5 |
H10B—C10A—H10C | 109.5 | H10E—C10B—H10F | 109.5 |
C8A—C11A—H11A | 109.5 | C8B—C11B—H11D | 109.5 |
C8A—C11A—H11B | 109.5 | C8B—C11B—H11E | 109.5 |
H11A—C11A—H11B | 109.5 | H11D—C11B—H11E | 109.5 |
C8A—C11A—H11C | 109.5 | C8B—C11B—H11F | 109.5 |
H11A—C11A—H11C | 109.5 | H11D—C11B—H11F | 109.5 |
H11B—C11A—H11C | 109.5 | H11E—C11B—H11F | 109.5 |
C13A—C12A—C6A | 112.27 (9) | C13B—C12B—C15B | 107.54 (10) |
C13A—C12A—C15A | 107.87 (9) | C13B—C12B—C6B | 112.18 (9) |
C6A—C12A—C15A | 110.06 (10) | C15B—C12B—C6B | 109.49 (9) |
C13A—C12A—C14A | 107.79 (10) | C13B—C12B—C14B | 108.16 (9) |
C6A—C12A—C14A | 108.50 (9) | C15B—C12B—C14B | 110.12 (9) |
C15A—C12A—C14A | 110.33 (9) | C6B—C12B—C14B | 109.32 (9) |
C12A—C13A—H13A | 109.5 | C12B—C13B—H13D | 109.5 |
C12A—C13A—H13B | 109.5 | C12B—C13B—H13E | 109.5 |
H13A—C13A—H13B | 109.5 | H13D—C13B—H13E | 109.5 |
C12A—C13A—H13C | 109.5 | C12B—C13B—H13F | 109.5 |
H13A—C13A—H13C | 109.5 | H13D—C13B—H13F | 109.5 |
H13B—C13A—H13C | 109.5 | H13E—C13B—H13F | 109.5 |
C12A—C14A—H14A | 109.5 | C12B—C14B—H14D | 109.5 |
C12A—C14A—H14B | 109.5 | C12B—C14B—H14E | 109.5 |
H14A—C14A—H14B | 109.5 | H14D—C14B—H14E | 109.5 |
C12A—C14A—H14C | 109.5 | C12B—C14B—H14F | 109.5 |
H14A—C14A—H14C | 109.5 | H14D—C14B—H14F | 109.5 |
H14B—C14A—H14C | 109.5 | H14E—C14B—H14F | 109.5 |
C12A—C15A—H15A | 109.5 | C12B—C15B—H15D | 109.5 |
C12A—C15A—H15B | 109.5 | C12B—C15B—H15E | 109.5 |
H15A—C15A—H15B | 109.5 | H15D—C15B—H15E | 109.5 |
C12A—C15A—H15C | 109.5 | C12B—C15B—H15F | 109.5 |
H15A—C15A—H15C | 109.5 | H15D—C15B—H15F | 109.5 |
H15B—C15A—H15C | 109.5 | H15E—C15B—H15F | 109.5 |
O1A—C1A—C2A—O2A | −0.23 (14) | O1B—C1B—C2B—O2B | 2.92 (13) |
C6A—C1A—C2A—O2A | −179.75 (9) | C6B—C1B—C2B—O2B | −175.97 (8) |
O1A—C1A—C2A—C3A | 179.77 (9) | O1B—C1B—C2B—C3B | −179.19 (9) |
C6A—C1A—C2A—C3A | 0.25 (16) | C6B—C1B—C2B—C3B | 1.93 (15) |
O2A—C2A—C3A—C4A | −177.43 (9) | O2B—C2B—C3B—C4B | 179.78 (9) |
C1A—C2A—C3A—C4A | 2.57 (15) | C1B—C2B—C3B—C4B | 2.04 (15) |
O2A—C2A—C3A—C7A | 3.57 (14) | O2B—C2B—C3B—C7B | 2.22 (14) |
C1A—C2A—C3A—C7A | −176.43 (9) | C1B—C2B—C3B—C7B | −175.52 (10) |
C2A—C3A—C4A—C5A | −2.79 (14) | C2B—C3B—C4B—C5B | −3.52 (14) |
C7A—C3A—C4A—C5A | 176.12 (10) | C7B—C3B—C4B—C5B | 173.84 (10) |
C2A—C3A—C4A—C8A | 176.94 (9) | C2B—C3B—C4B—C8B | 175.97 (9) |
C7A—C3A—C4A—C8A | −4.15 (16) | C7B—C3B—C4B—C8B | −6.67 (16) |
C3A—C4A—C5A—C6A | 0.36 (15) | C3B—C4B—C5B—C6B | 1.28 (15) |
C8A—C4A—C5A—C6A | −179.38 (9) | C8B—C4B—C5B—C6B | −178.23 (9) |
O1A—C1A—C6A—C5A | 177.85 (9) | O1B—C1B—C6B—C5B | 177.04 (9) |
C2A—C1A—C6A—C5A | −2.65 (15) | C2B—C1B—C6B—C5B | −4.10 (14) |
O1A—C1A—C6A—C12A | −3.19 (15) | O1B—C1B—C6B—C12B | −4.00 (14) |
C2A—C1A—C6A—C12A | 176.32 (9) | C2B—C1B—C6B—C12B | 174.86 (9) |
C4A—C5A—C6A—C1A | 2.40 (16) | C4B—C5B—C6B—C1B | 2.58 (15) |
C4A—C5A—C6A—C12A | −176.56 (10) | C4B—C5B—C6B—C12B | −176.38 (9) |
C2A—C3A—C7A—O3A | −2.33 (16) | C2B—C3B—C7B—O3B | −1.77 (17) |
C4A—C3A—C7A—O3A | 178.74 (10) | C4B—C3B—C7B—O3B | −179.20 (10) |
C5A—C4A—C8A—C9A | 3.81 (14) | C5B—C4B—C8B—C10B | 123.69 (11) |
C3A—C4A—C8A—C9A | −175.91 (10) | C3B—C4B—C8B—C10B | −55.79 (13) |
C5A—C4A—C8A—C10A | −115.24 (11) | C5B—C4B—C8B—C11B | 6.45 (14) |
C3A—C4A—C8A—C10A | 65.03 (13) | C3B—C4B—C8B—C11B | −173.02 (10) |
C5A—C4A—C8A—C11A | 121.69 (11) | C5B—C4B—C8B—C9B | −112.06 (12) |
C3A—C4A—C8A—C11A | −58.03 (13) | C3B—C4B—C8B—C9B | 68.47 (14) |
C1A—C6A—C12A—C13A | −178.10 (10) | C1B—C6B—C12B—C13B | −176.58 (9) |
C5A—C6A—C12A—C13A | 0.83 (15) | C5B—C6B—C12B—C13B | 2.35 (13) |
C1A—C6A—C12A—C15A | 61.73 (12) | C1B—C6B—C12B—C15B | −57.26 (12) |
C5A—C6A—C12A—C15A | −119.34 (11) | C5B—C6B—C12B—C15B | 121.66 (10) |
C1A—C6A—C12A—C14A | −59.08 (14) | C1B—C6B—C12B—C14B | 63.45 (12) |
C5A—C6A—C12A—C14A | 119.85 (11) | C5B—C6B—C12B—C14B | −117.63 (11) |
D—H···A | D—H | H···A | D···A | D—H···A |
O1A—H1A···O2A | 0.885 (15) | 2.169 (15) | 2.6360 (10) | 112.4 (11) |
O2A—H2A···O3A | 1.154 (14) | 1.484 (14) | 2.5013 (10) | 142.7 (12) |
O1B—H1B···O2B | 0.883 (17) | 2.212 (16) | 2.6443 (10) | 109.7 (12) |
O2B—H2B···O3B | 0.974 (17) | 1.608 (16) | 2.5046 (10) | 150.9 (16) |
O1B—H1B···O3A | 0.883 (17) | 1.916 (17) | 2.7485 (11) | 156.4 (15) |
O1A—H1A···O3Bi | 0.885 (15) | 1.912 (15) | 2.7289 (11) | 152.9 (13) |
Symmetry code: (i) x, y−1, z. |
D—H···A | D—H | H···A | D···A | D—H···A |
O1A—H1A···O2A | 0.885 (15) | 2.169 (15) | 2.6360 (10) | 112.4 (11) |
O2A—H2A···O3A | 1.154 (14) | 1.484 (14) | 2.5013 (10) | 142.7 (12) |
O1B—H1B···O2B | 0.883 (17) | 2.212 (16) | 2.6443 (10) | 109.7 (12) |
O2B—H2B···O3B | 0.974 (17) | 1.608 (16) | 2.5046 (10) | 150.9 (16) |
O1B—H1B···O3A | 0.883 (17) | 1.916 (17) | 2.7485 (11) | 156.4 (15) |
O1A—H1A···O3Bi | 0.885 (15) | 1.912 (15) | 2.7289 (11) | 152.9 (13) |
Symmetry code: (i) x, y−1, z. |
Acknowledgements
This work was carried out in the framework of the Federal Target Program Scientific and Pedagogical Specialists of Innovative Russia for 2009–2013 (Contract GK_8460 from 31/08/2012 and Target aspirant agreement N14.132.21.1462 from 01/10/2012), and was supported financially by a Russian President Grant supporting scientific schools (NSh-1113/2012/3).
References
Albrecht, M., Janser, I., Kamptmann, S., Weis, P., Wibbeling, B. & Froehlich, R. (2004). Dalton Trans. pp. 37–43. Web of Science CSD CrossRef Google Scholar
Belmonte, M. M., Escudero-Adan, E. C., Martin, E. & Kleij, A. W. (2012). Dalton Trans. 41, 5193–5200. PubMed Google Scholar
Bruker (2008). SAINT, SMART and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA. Google Scholar
Furutachi, M., Chen, Z., Matsunaga, S. & Shibasaki, M. (2010). Molecules, 15, 532–544. Web of Science CrossRef CAS PubMed Google Scholar
Ng, S. W. (2005). Acta Cryst. E61, o2301–o2302. Web of Science CSD CrossRef CAS IUCr Journals Google Scholar
Sheldrick, G. M. (2008). Acta Cryst. A64, 112–122. Web of Science CrossRef CAS IUCr Journals Google Scholar
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2,3-Dihydroxybenzaldehyde is well known building-block for preparing Schiff-base ligands containining catechol fragment. These ligands are used for the synthesis of polynuclear metal complexes (Belmonte et al., 2012), supramolecular compounds (Albrecht et al., 2004) and catalysts (Furutachi et al., 2010). Here we report the crystal structure of the title compound (I).
The asymmetric unit of (I) contains two independent molecules (Fig. 1) with non-typical arrangement of tert-butyl groups (orto- and para- despite meta-position relative to CHO-group). All bond lengths and angles in (I) are normal and correspond to those observed in the related 2,3-dihydroxybenzaldehyde (Ng, 2005). The structure shows two types of O—H···O hydrogen bonds (Table 1) - intra- and intermolecular ones.
In the crystal, intermolecular O—H···O hydrogen bonds link alternating independent molecules into chains running in [010] (Fig. 1).