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Figure 1
Synthesis scheme to obtain the trans-isomer (±) 3. Reagents and conditions: (a) EtOH, r.t., 3 h; (b) homophthalic anhydride (2), conc. HOAc, 393 K, 5 h; EtOH, 8 M NaOH, r.t., 24 h. |
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Figure 1
Synthesis scheme to obtain the trans-isomer (±) 3. Reagents and conditions: (a) EtOH, r.t., 3 h; (b) homophthalic anhydride (2), conc. HOAc, 393 K, 5 h; EtOH, 8 M NaOH, r.t., 24 h. |