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Figure 2
Synthesis of 1, following the published procedure (Manjunatha et al., 2019 ). Reagents and solvents: (a) 4-(chloromethyl)-6-methoxy-5-methylpyrimidine, Cs2CO3, NaI, DMF; (b) LiOH, MeOH; (c) HATU, 2-fluoroethanamine, NMP. |
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