Figure 6
Structure overlay of the benzene rings of the two unique molecules of 1 (molecule 1: green; molecule 2: orange) and the benzene ring of CT319 in the crystal structure of its non-covalent complex with M. tuberculosis DprE1 (pink; PDB code: 4FDO; resolution: 2.4 Å), showing the similar conformations of the benzamide moieties. |