Mistletoe lectin I in complex with galactose and lactose reveals distinct sugar-binding properties

Mikeska, R.; Wacker, R.; Arni, R.; Singh, T.P.; Mikhailov, A.; Gabdoulkhakov, A.; Voelter, W.; Betzel, C.

doi:10.1107/S1744309104031501

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

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Figure 1
C^α trace of mistletoe lectin I. The A-chain in the upper right region is shown in dark green; the active-site residues Tyr76A, Tyr115A, Glu165A and Arg168A are shown in red in ball-and-stick representation. The B-chain in the lower left part is coloured yellow. Lactose is shown in ball-and-stick representation in purple in galactose-binding sites I and II. Glycosylation sites I in chain A and sites II to IV in chain B are indicated by their oligosaccharide structure visible in the electron density and are shown in ball-and-stick representation. Glycerol bound in the potential third galactose-binding site is shown in blue.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 61| Part 1| December 2005| Pages 17-25

doi:10.1107/S1744309104031501

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