Figure 8
(a) Galactose-binding site II of ricin as a ball-and-stick representation in blue. The N-acetylgalactosamine, shown as a turquoise ball-and-stick representation, was modelled into the binding pocket according to the ricin–lactose complex. Potential hydrogen bonds of the substituent on C2 are marked in blue dashed lines and distances are given in Å. (b) The galactose-binding site II of ML-I is shown in red as a ball-and-stick model. The N-acetylgalactosamine was modelled into the binding pocket according to the ML-I–galactose complex and shown as a blue ball-and-stick model. Potential hydrogen bonds and distances is are indicated as in (a). |