books received\(\def\hfill{\hskip 5em}\def\hfil{\hskip 3em}\def\eqno#1{\hfil {#1}}\)

ISSN: 2053-230X

Chemical genomics . By S. Jaroch and H. Weinmann (Editors). Ernst Schering Research Foundation Workshop 58. Pp. VII+173. Berlin: Springer-Verlag, 2006. Price 64.15 Euro. ISBN 103 540 27865 6

Keywords: book received.

Chemogenomics is an effort within pharmaceutical companies to integrate data on target protein sequences with molecular structures and selectivity data of small molecules. In contrast to the traditional focus on distinct targets, the chemogenomics approach considers target families and activity profiles. Contents: 1, Chemogenomics in drug discovery; 2, Chemogenomics strategies; 3, Chemogenomics approaches; 4, Diversity oriented synthesis; 5, Probing protein function with small molecules; 6, Tamoxifen-based probes for the study; 7, Protein structure similarity clustering; 8, Tackling the chemogenomic space.

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