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Figure 1
Structure of the active site of HCA II complexed with inhibitors. (a) Acetazolamide (AZM), (b) BB3, (c) TDM; (d) superimposition of all three: BB3, blue; TDM, red; AZM, green. The Zn atom is shown as a black sphere; side chains are as labeled. AZM coordinates were taken from PDB code 1yda (Nair et al., 1995 ![]() ![]() ![]() |