Trypanosoma brucei UDP-galactose-4′-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-α-d-galactose

Alphey, M.S.; Burton, A.; Urbaniak, M.D.; Boons, G.-J.; Ferguson, M.A.J.; Hunter, W.N.

doi:10.1107/S1744309106028740

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

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Figure 1
(a) The epimerization catalyzed by TbGalE, interconverting UDP-Glc and UDP-Gal. The blue arrow indicates the P^β—O anomeric bond about which rotation occurs during catalysis. (b) The chemical structure of UDP-FGal.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 62| Part 9| August 2006| Pages 829-834

doi:10.1107/S1744309106028740

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