Figure 1
The structure of ECAO (PDB code 1dyu
) showing the substrate-entrance channel (magenta surface) and active site (Murray et al., 1999). The lower right panel is a more detailed view of the active site showing the TPQ, copper(II) ion, three coordinating histidine residues (sticks coloured by atom type) and the end of the substrate-entrance channel (magenta surface). The substrate-entrance channel was calculated using CAVER (Petrek et al., 2006) and the image was prepared using PyMOL (DeLano, 2002). |