Figure 2
Structure-based alignment of NMB1585 with MarR sequences of known structure. The sequences of NMB1585 (N. meningitidis), MarR (E. coli; PDB code 1jgs
), OhrR (B. subtilis; PDB code 1z91
) and MTH313 (M. thermoautotrophicum; PDB code 3bpv
) were aligned using ClustalW and displayed with secondary structures using ESPript2.2. The residues proposed to be involved in DNA binding (Gln58, Thr59, Ser61, Arg83) and ligand binding (Tyr29, Trp53) are indicated by arrows. |