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Figure 4
Conserved residues in YP_749275.1 and YP_001095227.1. (a) A sequence alignment with other members of the PFAM PB000640 family (not shown) reveals several conserved residues (marked in grey boxes). Residues from the binding cavity are colored blue and residues that are predicted to penetrate to the lipid bilayer are colored red. These residues are indicated on the structure in (b) for YP_001095227.1 and (c) for YP_749275.1. The main cluster of conserved residues from strand β1 and helices α1 and α2 is shown in purple. The protein backbone is shown in a cartoon representation. The calculated membrane boundary is shown by grey dots. A few additional nonconserved residues involved in hydrophobic interactions (Leu8, Leu74 and Trp65) in YP_749275.1 are shown in orange.

ISSN: 2053-230X
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