Figure 4
Schematic of the structural and sequence relationships between families belonging to the BLIP-like superfamily. PepSY, DUF2487, BLIP and SmpA_OmlA structures were rendered using OpenAstexViewer (Hartshorn, 2002). The structure is colored from blue at the N-terminus to orange at the C-terminus. For each family, a box indicates the portion of the representative structure that corresponds to a single copy of the domain. The tandem domain arrangement is obvious for DUF2847 and BLIP, but less so for PepSY owing to the different rotation of the second domain with respect to the first copy of the domain. SmpA_OmlA only has a single copy of the domain. No three-dimensional structure is known for DUF3192. Relationships between the families that could be identified using sequence-based methods only are shown as gray arrows, whereas strong structural similarity is indicated by solid black arrows and weak structural similar by dashed black arrows. |