Figure 2
TOPSAN has been developed on the MindTouch Deki framework, which adheres to open standards and has a reasonable set of features that could be readily modified for our exploratory platform. A remote application TopsanApp uses the Deki's API to generate and populate TOPSAN entries automatically with content from a variety of primary and derived data sources. Custom extensions allow real-time feeds from external data sources, which include CATH, SCOP, PubMed and UniProt, as well as SEED (Overbeek et al., 2005), KEGG (Ogata et al., 1999), PFAM (Sonnhammer et al., 1997) and STRING (Snel et al., 2000). The wiki interface allows community-based annotations, which can be exported through API access. UCSD's CAVE display imports TOPSAN annotations in a structure-gallery wall display. PFAM 24.0 has integrated TOPSAN content on PFAM structure pages. |