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Figure 12
Catalytic site of the mouse γ-glutamylamine cyclotransferase A2LD1. (a) Catalytic site residues of A2LD1 represented by a bundle of the five lowest-energy NMR conformers. Cyan coloring highlights residues that form hydrogen bonds with the ligands in the crystal structures. (b) Superposition of the crystal structures of A2LD1 in complex with formate (green) and human GGACT in complex with 5-oxo-L-α-proline (magenta; PDB code 3juc ; Oakley et al., 2010 ![]() |