Structure of a tryptophanyl-tRNA synthetase containing an iron–sulfur cluster

Han, G.W.; Yang, X.-L.; McMullan, D.; Chong, Y.E.; Krishna, S.S.; Rife, C.L.; Weekes, D.; Brittain, S.M.; Abdubek, P.; Ambing, E.; Astakhova, T.; Axelrod, H.L.; Carlton, D.; Caruthers, J.; Chiu, H.-J.; Clayton, T.; Duan, L.; Feuerhelm, J.; Grant, J.C.; Grzechnik, S.K.; Jaroszewski, L.; Jin, K.K.; Klock, H.E.; Knuth, M.W.; Kumar, A.; Marciano, D.; Miller, M.D.; Morse, A.T.; Nigoghossian, E.; Okach, L.; Paulsen, J.; Reyes, R.; van den Bedem, H.; White, A.; Wolf, G.; Xu, Q.; Hodgson, K.O.; Wooley, J.; Deacon, A.M.; Godzik, A.; Lesley, S.A.; Elsliger, M.-A.; Schimmel, P.; Wilson, I.A.

doi:10.1107/S1744309110037619

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 3
Model of the TmTrpRS–tRNA complex. (a) Overall view of the complex. TmTrpRS is shown as a gray-blue ribbon and tRNA as an orange trace. The anticodon bases, Cys266 and the [4Fe–4S] cluster are shown as stick models. Close-up view of the interaction of TrpRS–tRNA with the anticodon (CCA) region. Cyt34 of the tRNA molecule interacts with the iron of the cluster via Cys266. The model was based on the structure of the human TrpRS–tRNA complex (PDB code 1r6t ). (b) Close-up view of the loop conformation of TmTrpRS (pink) near the [4Fe–4S] cluster (pink sticks) compared with the helix (Asp382–Asn389) of the human TrpRS–tRNA complex (gray–blue) and BsTrpRS (yellow).

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 66| Part 10| September 2010| Pages 1326-1334

doi:10.1107/S1744309110037619

Follow Acta Cryst. F

Search term		doi		Advanced search
Author		volume	page