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Figure 4
A Cα trace of one LdPTR1 subunit (cyan) overlaid with an LmPTR1 subunit (PDB code 1e7w ; Gourley et al., 2001BB12; black). The sulfate ion bound to LdPTR1 is shown as yellow sticks, while the NADPH and methotrexate binding to LmPTR1 are depicted as red and orange sticks, respectively. The β6–α6 loop of the LmPTR1 model is marked. This loop is absent from LdPTR1. The β5–α5 substrate-binding loop adopts different positions in the two structures.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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