Figure 2
Tetrameric glutaryl-CoA dehydrogenase from B. pseudomallei (BpGCDH; PDB entry 3eom
) overlaid with one protomer of human glutaryl-CoA dehydrogenase (PDB entry 1sir
; Fu et al., 2004). The BpGCDH tetramer (green, cyan, magenta and yellow) is in the apo state, while the hGCDH protomer (gray) is in a ternary complex with the cofactor FAD (black) and the substrate mimic S-4-nitrobutyryl-CoA (NBC; white). |