Figure 6
Active sites of apo BpGCDH (green; PDB entry 3eom
) overlaid with complexes containing bound fragments, represented as lines. (a) FOL239 (yellow; PDB entry 3eon
) was observed in one active site per tetramer. (b) FOL544 (cyan; PDB entry 3d6b
) was also observed in one active site per tetramer. (c) FOL6421 (magenta; PDB entry 3gnc
) was observed in all four active sites of tetrameric BpGCDH. (d) One molecule of FOL680 (orange; PDB entry 3gqt
) was observed in one active site as shown, while two were observed in another active site (Fig. 5), resulting in three molecules of FOL680 per BpGCDH tetramer. |