Figure 4
Alignment of solved structures of bacterial 3-ketoacyl-(ACP) reductases. Multiple sequence and secondary-structure alignment of bacterial orthologs. Numbering along the top is based on the alignment consensus. Predicted α-helices, β-strands, coils and turns are shown as pink cylinders, yellow arrows, grey corkscrews and blue curved arrows, respectively. Sequences are taken from the PDB. From top to bottom: E. coli, 1i01
(Price et al., 2001); M. tuberculosis, 1uzm
(Cohen-Gonsaud et al., 2002); Pseudomonas aeruginosa, 2b4q
(Miller et al., 2006); Aquifex aeolicus, 2pnf
(Q. Mao, R. Huether, W. L. Duax & T. C. Umland, unpublished work); R. prowazekii, 3f9i
(this work); Burkholderia pseudomallei, 3ftp
(Seattle Structural Genomics Center for Infectious Disease, unpublished work); Bartonella henselae, 3grp
(B. L. Staker, unpublished work); Brucella melitensis, 3n74
(Seattle Structural Genomics Center for Infectious Disease, unpublished work). This figure was prepared with Geneious (Drummond et al., 2010). |