 | Acta Crystallographica Section F Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS |
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![[Figure 1]](hv5218fig1mag.jpg)
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Figure 1
Chemical structures of adenosine-5′-triphosphate (ATP), Fasudil and H-89 in similar orientations with respect to the ATP pocket (hinge region at the left). The isoquinoline portion of H-89 is highlighted in blue, the sulfonamide portion in green and the bromobenzene moiety in red. The numbering of the H-89 molecule refers to C3 and N4, consistent with the designation of the atoms in the structure 3vqh . `PKA' refers to cAMP-dependent protein kinase catalytic subunit α isoform 1 and `ROCK2' to Rho kinase α. Affinity values were taken from the literature: *, Rajagopalan et al. (2010  ); †, Gassel et al. (2003); ‡, Yano et al. (2008); §, Engh et al. (1996). |
![[Figure 1]](hv5218fig1.jpg)
| STRUCTURAL BIOLOGY COMMUNICATIONS |
ISSN: 2053-230X
