The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery

Moynie, L.; Schnell, R.; McMahon, S.A.; Sandalova, T.; Boulkerou, W.A.; Schmidberger, J.W.; Alphey, M.; Cukier, C.; Duthie, F.; Kopec, J.; Liu, H.; Jacewicz, A.; Hunter, W.N.; Naismith, J.H.; Schneider, G.

doi:10.1107/S1744309112044739

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

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Figure 2
(a) Schematic view of the structure of PA2169, a protein of unknown function. The dotted line indicates the flexible loop that is not well defined in electron density. (b) Surface representation of PA2169 with residues colour-coded according to sequence conservation from white (not conserved) to cyan (invariant). (c) View of the potential metal-binding site in PA2169 comprising residues Glu102, Asp106 and His139.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 69| Part 1| December 2013| Pages 25-34

doi:10.1107/S1744309112044739

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