Figure 1
Electron-density maps. (a) Electron density representing the uracil molecule and nearby residues in the A subunit of the D4–uracil complex. Residues within 12 Å distance of the uracil base are shown as thin sticks and active-site residues are shown as thick sticks and labeled. The map shown is a σA-weighted 2mFo − DFc map contoured at 1.5σ, where m is the figure of merit and D is the σA weighting factor. (b) Electron density representing the uracil molecule in the A subunit is shown. The electron-density map is an mFo − DFc map (m is the figure of merit and D is the σA weighting factor) calculated after the removal of uracil molecules from each subunit. The displayed map is contoured at 3σ and covers a distance of 8 Å around the uracil base. |