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Figure 5
Comparison of E. coli UNG and D4. (a) Stereo diagram showing a superposition of amino-acid residues within 4.5 Å distance of uracil in E. coli UNG (PDB entry 2eug ) and D4. Amino-acid residues are shown as stick models. Color code for D4: N, blue; O, red; C, yellow; E. coli UNG is shown in cyan. (b) Stereo drawing showing superposition of the uracil-specificity motif, catalytic water loop and leucine-intercalation loop in E. coli UNG (PDB entry 2eug ) and the corresponding regions in D4 (subunit B). The active-site histidines His187 of E. coli UNG and His181 of D4 are labeled. Color code for D4: N, blue; O, red; C, green in D4; E. coli UNG is shown in magenta

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Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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