Figure 3
Overall structure of the Siah1 dimer. The figure shows the 1.58 Å resolution structure. The zinc-finger subdomains are coloured red and blue, while the substrate-binding domains (SBDs) of monomers A and B are coloured green and orange, respectively. The N- and C-termini are labelled. The Zn2+ ions are shown as grey spheres and the disordered loops are marked with asterisks. |