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Figure 9
The curve shown here represents a typical solubility curve for a protein and divides, as in Fig. 2[link], the region of undersaturation from that of supersaturation. It also illustrates the existence of the classical `salting-in' and `salting-out' regions for the protein. By taking advantage of these latter effects, supersaturation may be achieved by equilibrating a system from a point of maximum solubility (P0) to one of reduced solubility (P1 or P2) by adjusting the precipitant concentration.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 70| Part 1| December 2014| Pages 2-20
doi:10.1107/S2053230X13033141
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