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Figure 4
p202 HINa and AIM2 HIN bind to dsDNA using completely different interfaces. Molecule A of p202 HINa is positioned in the same orientation as one of the AIM2 HIN molecules (megenta) in the AIM2 HIN–dsDNA structure (PDB entry 3rn2 ). (a) The DNA-binding interface (left) and its opposite surface (right) in p202 HINa. The left and right panels show surface representations of molecule A (coloured according to electrostatic potential: positive, blue; negative, red) in views related to the middle ribbon diagram by 90° clockwise or anticlockwise rotations around a vertical axis. (b) The DNA-binding interface (right) and its opposite surface (left) in AIM2 HIN. The two AIM2 HIN molecules bound to dsDNA within the asymmetric unit are coloured pink and brown, respectively, and the surface representations are generated from the boxed AIM2 HIN molecule.

ISSN: 2053-230X
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