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Figure 1
Catabolic processes involving allophanate hydrolase (AH). The cyanuric acid catabolic pathway involves ring opening of cyanuric acid by cyanuric acid hydrolase (CH), spontaneous decarboxylation of the product (1-carboxybiuret) and deamination of biuret by biuret hydrolase (BH) to produce allophanate. The urea catabolic pathway involves ATP-dependent urea carboxylation by urea carboxylase (UC) to produce allophanate. Both pathways then depend upon allophanate deamination by allophanate hydrolase to avoid spontaneous decarboxylation (and urea formation).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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