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Figure 3
Sampling of variables in two dimensions. Random sampling (blue stars) is considered to be among the best approaches for crystallization success. While random sampling covers a broad range of parameter space, sparse-matrix sampling (white hexagons) is a random screen that focuses on variables known to have had past success. An orthogonal array (yellow circles) is a symmetric sampling of random space. Footprint screen (orange squares) sampling begins by incrementally searching in a narrow range of variables. Adapted from Segelke (2001BB122).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 70| Part 7| July 2014| Pages 835-853
https://doi.org/10.1107/S2053230X1401262X
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