Figure 1
Binding to His15 shows a chemically transformed cisplatin, namely transiodoplatin. (a, b) The molecule A binding site shown in two different views. The 2Fo − Fc electron-density map (blue) is contoured at 1.5 r.m.s. and the anomalous difference electron-density map (orange) is contoured at 3σ. The Pt atom is shown in purple, the iodines are in yellow, the chlorine is in grey, C atoms are in green and N atoms are in blue. |