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Figure 5
Analysis of global conformation changes between transketolases generated by ProSMART and visualized in PyMOL. The residues are coloured according to the similarity of their local coordinate frames. Residues that relate closely to the rigid substructure are coloured red, gradually fading to white for regions that adopt a different global conformation. (a) LsTktA (PDB entry 4c7x ), (b) superimposition of nonhuman transketolases (PDB entries 1ay0 , 1r9j , 3kom , 3upt , 1itz , 2e6k , 3m7i , 1qgd , 3hyl and 3rim ) and (c) human transketolase (PDB entry 3mos ).

ISSN: 2053-230X
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