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Figure 3
Putative binding site of Spt16 NTD for the H4 N-terminal tail. (a) Superimposition of Spt16 NTD structures from human (blue), S. cerevisiae (green; PDB entry 3bip ) and S. pombe (orange; PDB entry 3cb5 ) showing a close-up view of the H4 N-terminal tail-binding site on the N-lobe. The Ser83 and Lys86 side chains located on the α3 helix on the S. pombe Spt16 NTD structure and the corresponding Ser and Lys in human and S. cerevisiae Spt16 NTD are indicated. (b) Overall structure of human Spt16 NTD showing the location of the α3 helix.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 72| Part 2| January 2016| Pages 121-128
doi:10.1107/S2053230X15024565
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