Figure 4
ITC profiles of human Spt16 NTD against (a) histone H4 N-terminal tail, (b) histone H3 N-terminal tail, (c) H2A/H2B and (d) H3/H4. (a, b) Raw data for the N-terminal peptide from H4 (blue) and H3 (green), respectively, titrated into human Spt16 NTD. (c) ITC profile showing raw data (upper panel) and integrated raw data (lower panel) for the titration of human Spt16 NTD against H2A/H2B. (d) ITC profile showing raw data (upper panel) and integrated data (lower panel) for the titration of human Spt16 NTD against H3/H4. |