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Figure 5
Electrostatic surface potential (−3 to 3kT) comparison of human, S. pombe and S. cerevisiae Spt16 NTD. Electrostatic surface representations of (a) human, (b) S. pombe and (c) S. cerevisiae Spt16 NTD in different views generated using APBS (Baker et al., 2001BB2) in PyMOL (Schrödinger). S. pombe Spt16 NTD reveals a larger acidic surface at the conserved pocket than that observed in S. cerevisiae and human Spt16 NTD. The left panel is in the same orientation as in Fig. 2[link](a); the middle and right panels are rotated 90 and 180° about the horizontal axis, respectively. (d, e) Top and bottom view, respectively, of human Spt16 NTD as shown in the left panel in (a). The arrow indicates the location of the conserved pocket.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 72| Part 2| January 2016| Pages 121-128
doi:10.1107/S2053230X15024565
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