Figure 1
Overall structure of Mi-IclR. (a) A subunit consists of a DNA-binding domain (DBD) at the N-terminus and a substrate-binding domain (SBD) at the C-terminus. Secondary structures are coloured cyan and magenta for α-helices and β-sheets, respectively. (b) Front view (top) and top view from the SBD side (bottom) of the homodimer conformation of Mi-IclR. One of the subunits in the dimer is coloured blue, cyan and pink for the SBD, the linker and the DBD, respectively. (c) Top view (left) and side view (right) of the homotetramer structure of Mi-IclR. The four subunits are shown in different colours, and the DBDs are indicated in the cognate pale colours. |