Figure 4
Structure of FtASADH in surface representation. Blue (chain B) and red (chain A) regions correspond to residues that are conserved in the ASADHs from V. cholerae, E. coli, P. aeruginosa, H. influenzae, B. thailandensis and F. tularensis that have had their structures determined and belong to the `aspartate semialdehyde dehydrogenases I' cluster. NADP+ (yellow spheres) is modeled using the structure of H. influenzae ASADH (PDB entry 1pqu). The active-site Cys135 is shown in green. This figure was prepared with PyMOL (DeLano, 2002). |