Figure 3
Structural comparison with tetrameric full-length HRSV M2–1 and HMPV M2–1. (a) Superposition of the HRSV M2–1 RBD (blue) with full-length HRSV M2–1. (b) Superposition of the HRSV M2–1 RBD (blue) with full-length HMPV M2–1. Within the full-length proteins, the tetramerization domains are coloured yellow, zinc-binding domains orange and the RBD core domains grey. Zn2+ ions are displayed as magenta spheres. The C-terminal tail (residues 178–185) in the HRSV M2–1 RBD structure that is not present in the tetrameric crystal structure is displayed as sticks and coloured cyan. |