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Figure 4
Comparison of MmGADL1 with other PLP-dependent decarboxylases. (a) Sequence alignment of MmGADL1 with homologous structures. The conserved PLP-modified lysine is indicated (green triangle). Secondary structure elements and sequence numbering correspond to MmGADL1. (b) Stereo image of a structural superposition of PLP-dependent decarboxylase homologues, viewed towards the active-site cavity. The covalently linked MmGADL1 PLP moiety is depicted as red spheres. The black arrow shows the position of the active-site-covering loop, which is disordered in the MmGADL1 crystal structure. (c) Conservation of PLP conformation in the superposed PLP-dependent decarboxylase structures.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 74| Part 1| January 2018| Pages 65-73
https://doi.org/10.1107/S2053230X17017848
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