Figure 1
IBD domain-swapped dimer (chain G, red; chain H, blue) viewed perpendicular to the local twofold axis (top). The IBD domain from the human integrase complex (PDB entry 2b4j) is shown in yellow (left), together with its superposition on chain H (bottom). All helices superimpose well, with the only significant disruption in loop 4–5. Figures were prepared with UCSF Chimera (Pettersen et al., 2004). |