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Figure 4
Comparison of the Kelch domains of NS1-BP and its homologues. (a, b) Superposition of the Kelch domain of NS1-BP (grey) on those of KEAP1 (PDB entry 1zgk; magenta) and KBTBD (PDB entry 4asc; cyan). The six Kelch repeats are numbered 1–6. The comparison highlights the differences in the B–­C loop regions. (c) Structure-based sequence alignment of the second and the sixth Kelch-repeat motifs from the Kelch domains of NS1BP, KEAP1 and KBTBD5. Conserved regions are shown in blue boxes. Highly conserved residues are in white on a red background; moderately conserved residues are in red. Sequence alignment was performed using ESPript (Robert & Gouet, 2014BB13).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 74| Part 3| March 2018| Pages 174-178
https://doi.org/10.1107/S2053230X18001577
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