Figure 3
The four GD3 glycan-binding sites as seen in the BKPyV VP1–GD3 crystal (Neu et al., 2013). Only the GD3 orientation seen in (a) and (b) is compatible with the STD-NMR difference spectrum shown in Fig. 4. Residue Lys68 is highlighted in (a). C atoms for which the attached protons are explicitly discussed in §4.1 are labelled where modelled. |