Figure 2
Overall arrangement of the Fc structure, with subunit A colored blue and subunit B in green. The N-terminal location of the hinge is at the top center and the C-termini are shown at the bottom. Each chain comprises two domains labeled CH2 and CH3. Glycans are shown centrally as bright sticks. Each subunit has seven sites of commonly observed allotypic variation, which are also shown as sticks (see §3). All figures were prepared using PyMOL (DeLano, 2002). |