Figure 3
Solvent-accessibility of helix α1 in crystals of the MBP-DUSP1 CD–DARPin off7 complex. (a) Surface representation of the DUSP1 CD showing the location of helix α1 (pink) with respect to the active site (yellow). (b) Crystal packing of the MBP-DUSP1 CD–DARPin off7 complex. MBP, DARPin off 7 and DUSP1 CD residues are colored green, pink and cyan, respectively. Helix α1 residues are shown as red spheres. |